Test ID 60506 Cutaneous Anaplastic Large Cell Lymphoma, 6p25.3 (IRF4) Rearrangement, FISH, Tissue
Providing potential prognostic information in patients with documented systemic anaplastic lymphoma kinase-negative anaplastic large cell lymphoma
Fluorescence In Situ Hybridization (FISH)
Reporting NameIRF4, 6p25.3, FISH
Provide a pathology report with each tissue specimen. The laboratory will not reject a specimen that arrives without this information, but will hold the specimen until a pathology report is received.
Submit only 1 of the following specimens:
Specimen Type: Lymph node
Preferred: Tissue block
Collection Instructions: Formalin-fixed, paraffin-embedded (FFPE) tumor tissue block. Include 1 hematoxylin and eosin (H and E)-stained slide.
Collection Instructions: For each probe set ordered, 2 unstained consecutive tissue sections cut at 5 microns and placed on positively charged microscope slides. Include 1 H and E-stained slide.
Specimen Minimum Volume
Formalin-fixed paraffin-embedded tissue block or 2 consecutive unstained 5-micron thick sections placed on positive-charged microscope slides and 1 hematoxylin and eosin-stained slide.
Specimen Stability Information
An interpretative report will be provided.
Day(s) and Time(s) Performed
Samples processed Monday through Sunday. Results reported Monday through Friday, 8 a.m.-5 p.m. CST.
Performing LaboratoryMayo Medical Laboratories in Rochester
CPT Code Information
88271 x 2-DNA probe, each
88275-Interphase in situ hybridization, 100 to 300 cells
88291-Interpretation and report
LOINC Code Information
|Result ID||Reporting Name||LOINC Code|
|20390||Ref Path/Phys Address||74221-3|
|20400||SP Signing Pathologist:||N/A|
|20401||*Previous Report Follows*||N/A|
Test ClassificationThis test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.
This test does not include a pathology consultation. If a pathology consultation is requested, 70012 / Pathology Consultation should be ordered and the appropriate FISH test will be ordered and performed at an additional charge.