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Test ID AHEP Acute Hepatitis Profile

Shipping Instructions


Necessary Information

Date of draw is required.

Specimen Required

Both 0.5 mL of refrigerated serum and 2.5 mL of frozen serum are required for this test.


Patient Preparation: For 12 hours before this test do not take multivitamins or dietary supplements containing biotin (vitamin B7), which is commonly found in hair, skin, and nail supplements and multivitamins.

Collection Container/Tube: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 3 mL

Collection Instructions: Spin down within 6 hours of draw.

Useful For

Differential diagnosis of recent acute viral hepatitis

Profile Information

Test ID Reporting Name Available Separately Always Performed
HAIGM Hepatitis A IgM Ab, S Yes Yes
HBAG HBs Antigen, S Yes Yes
HBIM HBc IgM Ab, S Yes Yes
HCVDX HCV Ab w/Reflex to HCV PCR, S Yes Yes

Testing Algorithm

If hepatitis C virus (HCV) antibody is reactive, then HCV RNA detection and quantification by real-time reverse transcription-PCR will be performed at an additional charge.


If hepatitis Bs antigen is reactive, then confirmation will be performed at an additional charge.


The following algorithms are available in Special Instructions:

-HBV Infection-Diagnostic Approach and Management Algorithm

-Hepatitis C: Testing Algorithm for Screening and Diagnosis

-Viral Hepatitis Serologic Profiles

Method Name

HAIGM: Chemiluminescent Microparticle Immunoassay (CMIA)

HBAG, HBIM, HCVQN: Chemiluminescence Immunoassay (CIA)

Reporting Name

Acute Hepatitis Profile

Specimen Type

Serum SST

Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated 5 days
Serum SST Frozen (preferred) 30 days
  Refrigerated  5 days

Reference Values

Hepatitis B Surface Antigen



Hepatitis B Surface Antigen Confirmation



Hepatitis B Core IgM Antibody



Hepatitis A IgM Antibody



Hepatitis C Antibody



HCV RNA Detection and Quantification by Real-Time RT-PCR



Interpretation depends on clinical setting. See Viral Hepatitis Serologic Profiles in Special Instructions.

Day(s) and Time(s) Performed

Monday through Saturday; Varies

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

80074-Acute hepatitis panel (all 4 initial tests are performed)

86709-Hepatitis A IgM antibody (if all 4 are not performed)

86705-Hepatitis B core antibody, IgM (if all 4 are not performed)

87340-Hepatitis B surface antigen (if all 4 are not performed)

86803-Hepatitis C antibody (if all 4 are not performed)

87522-Hepatitis C, quantification (if appropriate)

87341-HBsAg confirmation (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
AHEP Acute Hepatitis Profile In Process


Result ID Test Result Name Result LOINC Value
HCVA4 HCV Ab, S 13955-0
HBIM HBc IgM Ab, S 24113-3
H_BAG HBs Antigen, S 5196-1
HAIGM Hepatitis A IgM Ab, S 13950-1

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
HBGNT HBs Antigen Confirmation, S No No
HCVQN HCV RNA Detect/Quant, S Yes No