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Test ID C2 C2 Complement, Functional, with Reflex, Serum

Useful For

The investigation of a patient with a low (absent) hemolytic complement (CH50)

Method Name

C2: Automated Liposome Lysis Assay

C2AG: Radial Immunodiffusion-Binding Site

Reporting Name

C2 Complement,Functional,w/Reflex,S

Specimen Type

Serum Red

Specimen Required

Collection Container/Tube: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Immediately after drawing the specimen, place the tube on wet ice.

2. Spin down and separate serum from clot.

3. Immediately freeze specimen.

Additional Information: Fasting preferred.

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Frozen 21 days

Reference Values

25-47 U/mL

Day(s) and Time(s) Performed

Monday through Saturday; 3 p.m.

Performing Laboratory

Mayo Medical Laboratories in Rochester

CPT Code Information

86161-C2 complement, functional

86160-Complement C3 (if appropriate)

86160-Complement C4 (if appropriate)

86160-C2 Complement Antigen (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
C2 C2 Complement,Functional,w/Reflex,S 33408-6


Result ID Test Result Name Result LOINC Value
C2FX C2 Complement,Functional,S No LOINC Needed
INT53 Interpretation 69048-7

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
C4 Complement C4, S Yes No
C3 Complement C3, S Yes No
C2AG C2 Complement, Antigen, S No No

Testing Algorithm

If the C2 result is <15 U/mL, then C3, C4, and C2AG will be performed at an additional charge.