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Test ID DSG13 Desmoglein 1 (DSG1) and Desmoglein 3 (DSG3), IgG Antibodies, Serum

Useful For

Preferred screening test for patients suspected to have an autoimmune blistering disorder of the skin or mucous membranes (pemphigus)

 

As an aid in the diagnosis of pemphigus

 

Monitoring treatment response in patients with a confirmed diagnosis of pemphigus

Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)

Reporting Name

Desmoglein 1 and 3, S

Specimen Type

Serum


Specimen Required


Container/Tube: 

Preferred: Red top

Acceptable: Serum gel

Specimen Volume: 1 mL


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 7 days
  Frozen  14 days
  Ambient  36 hours

Reference Values

DESMOGLEIN 1

<14.0 U (negative)

14.0-20.0 U (indeterminate)

>20.0 U (positive)

 

DESMOGLEIN 3

<9.0 U (negative)

9.0-20.0 U (indeterminate)

>20.0 U (positive)

Day(s) and Time(s) Performed

Once per week, Monday through Friday, day of testing determined by laboratory

Performing Laboratory

Mayo Medical Laboratories in Rochester

CPT Code Information

83516 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
DSG13 Desmoglein 1 and 3, S 43309-4

 

Result ID Test Result Name Result LOINC Value
83680 DSG 1 43311-0
24027 DSG 3 43312-8

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.