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Test ID ECUMP Eculizumab Monitoring Panel, Serum

Useful For

Therapeutic drug monitoring of eculizumab


Test used to monitor therapy with the drug eculizumab

Profile Information

Test ID Reporting Name Available Separately Always Performed
C5FX C5 Complement, Functional, S Yes Yes
C5AG2 C5 Complement, Antigen, S Yes, (Order C5AG) Yes
INT86 ECUMP Interpretation No Yes

Method Name

C5AG2: Nephelometry

C5FX: Automated Liposome Lysis Assay

Reporting Name

Eculizumab Monitoring Panel, S

Specimen Type

Serum Red

Specimen Required

Patient Preparation:

1. Fasting preferred

2. Recommended timeframe for the blood draw is a trough, or immediately prior to next intravenous infusion.

Specimen Type: Serum

Collection Container/Tube: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1.5 mL

Collection Instructions:

1. Immediately after drawing the specimen, place the tube on wet ice.

2. Spin down and separate serum from clot.

3. Freeze specimen within 30 minutes.

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Frozen 14 days

Reference Values


10.6-26.3 mg/dL



29-53 U/mL

Day(s) and Time(s) Performed


Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

See Individual Test IDs

CPT Code Information

86160-Complement; antigen, each component

86161-Complement; functional activity, each component

LOINC Code Information

Test ID Test Order Name Order LOINC Value
ECUMP Eculizumab Monitoring Panel, S In Process


Result ID Test Result Name Result LOINC Value
C5FX C5 Complement, Functional, S 60472-8
C5AG2 C5 Complement, Antigen, S 4505-4
INT86 ECUMP Interpretation In Process