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Test ID FKMS Ketamine and Metabolite Screen, Serum/Plasma

Method Name

Gas Chromatography/Mass Spectrometry (GC/MS)

Reporting Name

Ketamine and Metabolite Screen

Specimen Type

Varies


Specimen Required


Submit only 1 of the following specimens:

 

Serum

Draw blood in a plain red-top tube(s), (Serum gel tube is not acceptable.) Spin down and send 5 mL serum refrigerated in a plastic preservative-free vial.

 

Plasma

Draw blood in a lavender-top (EDTA) tube(s) or green-top (heparin) tube(s), (Plasma gel tube is not acceptable.) Spin down and send 5 mL EDTA or heparinized plasma refrigerated in a plastic preservative-free vial.


Specimen Minimum Volume

2.4 mL

Specimen Stability Information

Specimen Type Temperature Time
Varies Refrigerated (preferred) 30 days
  Frozen  210 days
  Ambient  30 days

Reference Values

Reporting limit determined each analysis

Units: ng/mL

 

Ketamine:

            Synonyms:       Ketalar

 

 Reported levels during anesthesia: 500-6,500 ng/mL

 

Norketamine:

            Synonyms: Ketamine Metabolite

 

The intravenous administration of 2 mg/kg of Ketamine followed by continuous infusion of 41 mcg/kg/minute produced an average steady-state plasma concentration of 2,200 ng Ketamine/mL and an average peak Norketamine level of 1,050 ng/mL which occurred near the end of the 3 hour infusion.

Day(s) and Time(s) Performed

Tuesday, Thursday

Performing Laboratory

NMS Labs

CPT Code Information

80307 – Screen

80357 – Confirmation, if appropriate

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FKMS Ketamine and Metabolite Screen In Process

 

Result ID Test Result Name Result LOINC Value
Z3745 Ketamine Screen 19499-3
Z3746 Reporting Limit 19147-8
Z3747 Norketamine Screen In Process
Z3748 Reporting Limit 19147-8

Testing Algorithm

If Ketamine and Metabolite Screen is positive, then Ketamine and Metabolite Confirm (FKMSC) will be performed at an additional charge.

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
FKMSC Ketamine and Metabolite Confirm No No