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Test ID FLUC 5-Flucytosine, Serum

Useful For

Monitoring serum concentration during therapy

 

Evaluating potential toxicity

 

May be useful to evaluate patient compliance

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

5-Flucytosine, S

Specimen Type

Serum


Specimen Required


Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Specimen Volume: 0.5 mL

Collection Instructions: 

1. Serum for a peak level should be drawn 1 to 2 hours after oral dose or 30 minutes after intravenous infusion. Trough specimens should be drawn immediately prior to next scheduled dose.

2. Spin down within 2 hours of draw.


Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Frozen (preferred) 28 days
  Ambient  28 days
  Refrigerated  28 days

Reference Values

Therapeutic concentration:

Peak >25.0 mcg/mL (difficult infections may require higher concentrations)

Toxic concentration:

Peak >100.0 mcg/mL

Day(s) and Time(s) Performed

Tuesday, Thursday, 9 a.m.

Performing Laboratory

Mayo Medical Laboratories in Rochester

CPT Code Information

80299

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FLUC 5-Flucytosine, S In Process

 

Result ID Test Result Name Result LOINC Value
82741 5-Flucytosine, S 3639-2

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.