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Test ID P1433 14-3-3 Protein, Spinal Fluid

Useful For

Supporting, in conjunction with other tests, a diagnosis of Creutzfeldt-Jakob disease in patients with rapidly progressive dementia when other neurodegenerative conditions have been excluded.

Method Name

Immunochemiluminometric Assay (ICMA)

Reporting Name

14-3-3 Protein, CSF

Specimen Type

CSF


Specimen Required


Collection Container/Tube: Sterile vial

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Obtain aliquot from second collection vial.

2. Immediately place aliquot on ice.

Additional Information:

1. Specimens that have not been kept refrigerated, or which have been tested for other analytes previously, may give a false-positive result.

2. Hemolyzed specimens will give false-positive results. Specimens should be centrifuged to remove any red cells before shipping. The test will be canceled if there is any level of hemolysis present.


Specimen Minimum Volume

1 mL CSF on ice; Pediatric or minimum volume: 0.6 mL CSF on ice

Specimen Stability Information

Specimen Type Temperature Time
CSF Refrigerated (preferred) 7 days
  Frozen  90 days

Reference Values

Normal: ≤2.0 ng/mL

Elevated: >2.0 ng/mL

Day(s) and Time(s) Performed

Monday, Thursday: 2 p.m.

Performing Laboratory

Mayo Medical Laboratories in Rochester

CPT Code Information

83520

LOINC Code Information

Test ID Test Order Name Order LOINC Value
P1433 14-3-3 Protein, CSF 36924-9

 

Result ID Test Result Name Result LOINC Value
82528 14-3-3 Protein, CSF 36924-9

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.