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Test ID PNCSU Pain Clinic Survey, Urine

Useful For

Detecting drug use involving amphetamines, barbiturates, benzodiazepines, cocaine, opioids, phencyclidine, and tetrahydrocannabinol


This test is intended to be used in a setting where the test results can be used to make a definitive diagnosis.

Profile Information

Test ID Reporting Name Available Separately Always Performed
ADULT Adulterants Survey, U Yes Yes
TOPSU Targeted Opioid Screen, U Yes Yes
PNRCH Pain Clinic Immunoassay Panel, U No Yes

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
AMPHU Amphetamines Confirmation, U Yes No
COKEU Cocaine and metabolite Conf, U Yes No
BENZU Benzodiazepines Confirmation, U Yes No
BARBU Barbiturates Confirmation, U Yes No
PCPU Phencyclidine Confirmation, U Yes No
THCU Carboxy-THC Confirmation, U Yes No

Testing Algorithm

Testing begins with an adulterant survey. If the sample is found to be adulterated, testing will end, and the remaining tests will be canceled. If sample is normal or only diluted, remaining testing will continue. If immunoassay screen is positive, confirmation is performed. Confirmation with quantification of positives for amphetamines, barbiturates, benzodiazepines, cocaine and metabolites, phencyclidine, and tetrahydrocannabinol metabolite will be performed at an additional charge.

Method Name

ADULT, PNRCH: Screened by Immunoassay

TOPSU: Liquid Chromatography-Tandem Mass Spectrometry, High Resolution Accurate Mass (LC-MS/MS HRAM)

Reporting Name

Pain Clinic Survey, U

Specimen Type


Specimen Required

Collection Container/Tube: Plastic urine container

Submission Container/Tube: Plastic, 60-mL urine container (T-313)

Specimen Volume: 30 mL

Collection Instructions:

1. Collect a random urine specimen.

2. Submit 30 mL in 1 plastic bottle.

3. No preservative.

Additional Information:

1. No specimen substitutions.

2. Submitting less than 30 mL will compromise our ability to perform all necessary testing.

3. No STATS are accepted for this procedure.

4. For situations where chain of custody is required, a Chain-of-Custody Kit (T282) is available. For chain-of-custody testing, order PANOX / Pain Clinic Survey 10, Chain of Custody, Urine.

5. Additional drug panels and specific requests are available. Call Mayo Medical Laboratories at 800-533-1710 or 507-266-5700.

Specimen Minimum Volume

20 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 14 days
  Frozen  14 days
  Ambient  72 hours

Reference Values



Cutoff concentrations

Oxidants: 200 mg/L

Nitrites: 500 mg/L




Screening cutoff concentrations:

Amphetamines: 500 ng/mL

Barbiturates: 200 ng/mL

Benzodiazepines: 100 ng/mL

Cocaine (benzoylecgonine-cocaine metabolite): 150 ng/mL

Phencyclidine: 25 ng/mL

Tetrahydrocannabinol carboxylic acid: 50 ng/mL

This report is intended for use in clinical monitoring or management of patients. It is not intended for use in employment-related testing.



Not Detected


Cutoff concentrations:

Codeine: 25 ng/mL

Codeine-6-beta-glucuronide: 100 ng/mL

Morphine: 25 ng/mL

Morphine-6-beta-glucuronide: 100 ng/mL

6-monoacetylmorphine: 25 ng/mL

Hydrocodone: 25 ng/mL

Norhydrocodone: 25 ng/mL

Dihydrocodeine: 25 ng/mL

Hydromorphone: 25 ng/mL

Hydromorphone-3-beta-glucuronide: 100 ng/mL

Oxycodone: 25 ng/mL

Noroxycodone: 25 ng/mL

Oxymorphone: 25 ng/mL

Oxymorphone-3-beta-glucuronide: 100 ng/mL

Noroxymorphone: 25 ng/mL

Fentanyl: 2 ng/mL

Norfentanyl: 2 ng/mL

Meperidine: 25 ng/mL

Normeperidine: 25 ng/mL

Naloxone: 25 ng/mL

Naloxone-3-beta-glucuronide: 100 ng/mL

Methadone: 25 ng/mL

EDDP: 25 ng/mL

Propoxyphene: 25 ng/mL

Norpropoxyphene: 25 ng/mL

Tramadol: 25 ng/mL

O-desmethyltramadol: 25 ng/mL

Tapentadol: 25 ng/mL

N-desmethyltapentadol: 50 ng/mL

Tapentadol-beta-glucuronide: 100 ng/mL

Buprenorphine: 5 ng/mL

Norbuprenorphine: 5 ng/mL

Norbuprenorphine glucuronide: 20 ng/mL

Day(s) and Time(s) Performed

Monday through Friday; Varies

Performing Laboratory

Mayo Medical Laboratories in Rochester

CPT Code Information

PNRCH - 80307

TOPSU - 80364, G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PNCSU Pain Clinic Survey, U In Process


Result ID Test Result Name Result LOINC Value
42323 Codeine In Process
20606 Creatinine, U 2161-8
2573 Amphetamines 16369-1
2574 Barbiturates 16429-3
22312 Specific Gravity 5810-7
42324 Codeine-6-beta-glucuronide In Process
42325 Morphine In Process
23509 pH 2756-5
2575 Benzodiazepines 16195-0
21652 Cocaine 19360-7
23511 Oxidants 58714-7
42326 Morphine-6-beta-glucuronide In Process
42327 6-monoacetylmorphine In Process
23510 Nitrites 2657-5
2578 Phencyclidine 18392-1
2664 Tetrahydrocannabinol 19416-7
30914 Comment 48767-8
42328 Hydrocodone In Process
42329 Norhydrocodone In Process
42330 Dihydrocodeine In Process
42331 Hydromorphone In Process
42332 Hydromorphone-3-beta-glucuronide In Process
42333 Oxycodone In Process
42334 Noroxycodone In Process
42335 Oxymorphone In Process
42336 Oxymorphone-3-beta-glucuronide In Process
42337 Noroxymorphone In Process
42338 Fentanyl In Process
42339 Norfentanyl In Process
42340 Meperidine In Process
42341 Normeperidine In Process
42342 Naloxone In Process
42343 Naloxone-3-beta-glucuronide In Process
42344 Methadone In Process
42345 EDDP In Process
42346 Propoxyphene In Process
42347 Norpropoxyphene In Process
42348 Tramadol In Process
42349 O-desmethyltramadol In Process
42350 Tapentadol In Process
42351 N-desmethyltapentadol In Process
42352 Tapentadol-beta-glucuronide In Process
42353 Buprenorphine In Process
42354 Norbuprenorphine In Process
42355 Norbuprenorphine glucuronide In Process
65059 Opioid Interpretation 69050-3