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Test ID TCGBM T-Cell Receptor Gene Rearrangement, PCR, Bone Marrow

Useful For

Determining whether a T-cell population is polyclonal or monoclonal

Method Name

DNA Extracted for Analysis/Polymerase Chain Reaction (PCR)

(PCR is utilized pursuant to a license agreement with Roche Molecular Systems, Inc. and InVivoScribe Technologies.)

Reporting Name

T Cell Receptor Gene Rearrange, BM

Specimen Type

Bone Marrow

Specimen Required

Container/Tube:

Preferred: EDTA (lavender top)

Acceptable: ACD (yellow top)

Specimen Volume: 2 mL

Collection Instructions:

1. Invert several times to mix bone marrow.

2. Send specimen in original tube.


Shipping Instructions:

Specimen must arrive within 7 days (168 hours) of collection.



Necessary Information:

Include relevant clinical information and cytogenetics results, if available.


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Bone Marrow Ambient (preferred) 7 days
  Refrigerated  7 days

Reference Values

An interpretive report will be provided.

Positive, negative, or indeterminate for a clonal T-cell population

Day(s) and Time(s) Performed

Monday through Friday

Performing Laboratory

Mayo Medical Laboratories in Rochester

CPT Code Information

81340-TCB (T cell antigen receptor, beta) (eg, leukemia and lymphoma), gene rearrangement analysis to detect abnormal clonal population(s); using amplification methodology (eg, PCR)

81342-TCG@ (T cell receptor, gamma) (eg, leukemia and lymphoma), gene rearrangement analysis, evaluation to detect abnormal clonal population(s)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
TCGBM T Cell Receptor Gene Rearrange, BM In Process

 

Result ID Test Result Name Result LOINC Value
19957 Final Diagnosis: 34574-4

Test Classification

This test was developed using an analyte specific reagent. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

Testing Algorithm

See Malignant Lymphoma, Guideline for Bone Marrow Staging Studies in Special Instructions

Forms

1. Hematopathology Patient Information (T676) in Special Instructions

2. If not ordering electronically, complete, print, and send a Hematopathology/Cytogenetics Test Request Form (T726) with the specimen (http://www.mayomedicallaboratories.com/it-mmfiles/hematopathology-request-form.pdf)