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Test ID TXBU 11-Dehydro-Thromboxane B2, Urine

Useful For

Assessing if a patient will derive benefit from aspirin therapy


Determining an individual’s risk of coronary heart disease and stroke


Identifying the effectiveness of antiplatelet therapies

Method Name

TXBU: Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

AACT: Enzymatic Colorimetric Assay

Reporting Name

11-Dehydro-Thromboxane B2, U

Specimen Type


Specimen Required

Container/Tube: Plastic, 10-mL urine tube (T068)

Specimen Volume: 10 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.

Additional Information: Patient should not have taken nonsteroidal anti-inflammatory drugs within 72 hours or aspirin within 2 weeks prior to collection of a specimen.

Specimen Minimum Volume

5 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 7 days
  Frozen  90 days
  Ambient  7 days

Reference Values

≥18 years: 0-2,211 pg/mg creatinine

Reference values have not been established for patients who are <18 years of age.

Reference intervals apply to patients not taking agents known to influence platelet function (aspirin or other nonsteroidal anti-inflammatory drugs, thienopyridines, etc). Healthy individuals taking aspirin typically have 11-dehydro-thromboxane B2 concentrations below 500 pg/mg creatinine using this method.

Day(s) and Time(s) Performed

Wednesday; 8 a.m.

Performing Laboratory

Mayo Medical Laboratories in Rochester

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
TXBU 11-Dehydro-Thromboxane B2, U In Process


Result ID Test Result Name Result LOINC Value
83335 11-Dehydro-Thromboxane B2, U 49734-7

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

Testing Algorithm

When 11-dehydro-thromboxane B2 testing is performed, urine creatinine will always be performed at no additional charge.

Additional Tests

Test ID Reporting Name Available Separately Always Performed
AACT Creatinine, U No Yes


If not ordering electronically, complete, print, and send a Cardiovascular Test Request Form (T724) with the specimen (