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Test ID 21OH 21-Hydroxylase Antibodies, Serum


Advisory Information


Testing for auto-antibodies against 21-hydroxylase is recommended following confirmation of adrenal insufficiency to help differentiate between causes of primary adrenal insufficiency



Shipping Instructions


Ship serum specimen frozen



Specimen Required


Collection Container/Tube: 

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial to remove from cells or gel prior to shipping.


Useful For

Investigation of adrenal insufficiency

 

Aid in the detection of those at risk of developing autoimmune adrenal failure in the future

Highlights

Addison disease is the most frequent cause of primary adrenal insufficiency.

 

Auto-antibodies against 21-hydroxylase are present in up to 90% of Addison disease cases.

 

Measurement of anti-21-hydroxylase auto-antibodies is useful in the evaluation of the cause of established primary adrenal insufficiency.

Method Name

Enzyme-linked Immunosorbent Assay (ELISA)

Reporting Name

21-Hydroxylase Ab, S

Specimen Type

Serum

Specimen Minimum Volume

0.20 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Frozen 14 days

Reference Values

Negative

Day(s) and Time(s) Performed

Wednesday; 2 p.m.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved or is exempt by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

83516

LOINC Code Information

Test ID Test Order Name Order LOINC Value
21OH 21-Hydroxylase Ab, S 85363-0

 

Result ID Test Result Name Result LOINC Value
607788 21-Hydroxylase Ab, S 85363-0

NY State Approved

Yes