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Test ID 22C3 Programmed Death-Ligand 1 (PD-L1) (22C3), Semi-Quantitative Immunohistochemistry, Manual

Ordering Guidance

For information on selection of programmed cell death 1-ligand 1 (PD-L1) testing, see

Shipping Instructions

Attach the green pathology address label included in the kit to the outside of the transport container.

Necessary Information

A pathology/diagnostic report and a brief history, including primary site of neoplasm, are required.

Specimen Required

Specimen Type: Tissue

Supplies: Pathology Packaging Kit (T554)

Collection Instructions: Formalin-fixed, paraffin-embedded tissue block; or 3 unstained glass, "positively charged" slides with 4-microns formalin-fixed, paraffin-embedded tissue

Additional Information: One slide will be stained with hematoxylin and eosin and returned.

Useful For

Identification of neoplasms expressing programmed cell death 1-ligand 1 (clone 22C3)

Method Name

Immunohistochemistry (IHC)

Reporting Name

PD-L1 (22C3) SemiQuant IHC, Manual

Specimen Type


Specimen Stability Information

Specimen Type Temperature Time Special Container
Special Ambient (preferred)

Day(s) Performed

Monday through Friday

Report Available

5 to 7 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed using an analyte specific reagent. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
22C3 PD-L1 (22C3) SemiQuant IHC, Manual 85147-7


Result ID Test Result Name Result LOINC Value
603763 Interpretation 59465-5
603764 Participated in the Interpretation No LOINC Needed
603765 Report electronically signed by 19139-5
603766 Material Received 81178-6
603767 Disclaimer 62364-5
603768 Case Number 80398-1

NY State Approved



If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

Immunohistochemical (IHC)/In Situ Hybridization (ISH) Stains Request (T763)

Oncology Test Request (T729)