Sign in →

Test ID 23BPT 2,3-Dinor 11 Beta-Prostaglandin F2 Alpha, 24 Hour, Urine


Ordering Guidance


A 24-hour urine collection is the preferred specimen type, but a random specimen is also acceptable for 2,3-dinor 11beta-prostaglandin F2 alpha; order 23BPR / 2,3-Dinor 11 Beta-Prostaglandin F2 Alpha, Random, Urine.

 

If ordering this test with NMH24 / N-Methylhistamine, 24 Hour, Urine, both tests must be ordered under different order numbers. They cannot share an order number



Specimen Required


Patient Preparation: Patients taking aspirin or nonsteroidal anti-inflammatory drugs (NSAID) may have decreased concentrations of prostaglandin F2 alpha. If possible, discontinue for 2 weeks or 72 hours, respectively, prior to collecting a specimen.

Supplies: Plastic, 5-mL tube (T465)

Specimen Volume: 5 mL

Collection Instructions:

1. Collect urine for 24 hours.

2. No preservative preferred.

Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens in Special Instructions for multiple collections.


Useful For

Screening for mast cell activation disorders including systemic mastocytosis using 24-hour urine specimens

Highlights

2,3-Dinor-11beta-prostaglandin F2 alpha (2,3 BPG) is elevated in the urine of patients with systemic mastocytosis (SM).

 

This test should be used as a screening test for SM.

 

When 2,3 BPG is used in combination with urinary leukotriene E4 and N-methyl histamine, the sensitivity for SM detection increases to 90%.

Profile Information

Test ID Reporting Name Available Separately Always Performed
T23BP 2,3-dinor 11B-Prostaglandin F2a No Yes
CRT24 Creatinine, 24 HR, U No Yes

Method Name

T23BP: Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

CRT24: Enzymatic Colorimetric Assay

Reporting Name

2,3-dinor 11B-Prostaglandin F2a, U

Specimen Type

Urine

Specimen Minimum Volume

4 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 14 days
  Frozen  30 days
  Ambient  8 hours

Reference Values

<1802 pg/mg creatinine

Day(s) Performed

Monday, Thursday

Report Available

2 to 6 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

84150

LOINC Code Information

Test ID Test Order Name Order LOINC Value
23BPT 2,3-dinor 11B-Prostaglandin F2a, U 94381-1

 

Result ID Test Result Name Result LOINC Value
CR_A Creatinine, 24 HR, U 2162-6
603460 2,3-dinor 11B-Prostaglandin F2a 94381-1
TM10 Collection Duration 13362-9
VL8 Urine Volume 3167-4
CR_24 Creatinine Concentration, 24 HR, U 20624-3

NY State Approved

Yes

Urine Preservative Collection Options

Note: The addition of preservative or application of temperature controls must occur within 4 hours of completion of the collection.

 

Ambient

No

Refrigerate

Preferred

Frozen

OK

50% Acetic Acid

OK

Boric Acid

OK

Diazolidinyl Urea

No

6M Hydrochloric Acid

No

6M Nitric Acid

No

Sodium Carbonate

OK

Thymol

No

Toluene

No