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Test ID 6MAMM 6-Monoacetylmorphine (6-MAM), Confirmation, Meconium

Useful For

Detection of in utero heroin exposure up to 5 months before birth

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

6-MAM Confirmation, M

Specimen Type

Meconium


Ordering Guidance


For chain-of-custody testing, order MAMMX / 6-Monoacetylmorphine (6-MAM) Confirmation, Chain of Custody, Meconium.



Specimen Required


Supplies: Stool container, Small (Random), 4 oz (T288)

Container/Tube: Stool container

Specimen Volume: 1 g (approximately 1 teaspoon)

Collection Instructions:

1. Collect entire random meconium specimen.

2. Send specimen frozen. When refrigerated, a significant percentage of 6-MAM will convert to morphine in less than 24 hours.


Specimen Minimum Volume

0.3 g (approximately 1/4 teaspoon)

Specimen Stability Information

Specimen Type Temperature Time Special Container
Meconium Frozen 14 days

Reference Values

Negative

Positives are reported with a quantitative liquid chromatography-tandem mass spectrometry result.

Cutoff concentration: 5 ng/g

Day(s) Performed

Monday through Sunday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

80356

G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
6MAMM 6-MAM Confirmation, M 29345-6

 

Result ID Test Result Name Result LOINC Value
31874 6-Monoacetylmorphine 29345-6
31875 Interpretation 69050-3

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

Report Available

2 days

NY State Approved

Yes

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.