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HelpTest ID 7AC4 7AC4, Bile Acid Synthesis, Serum
Specimen Required
Patient Preparation:
1. Patient must fast for at least 12 hours prior to collection; fasting morning specimen is preferred.
2. Patient should not be taking bile acid sequestrants for 24 hours prior to collection or statins for 5 days prior to collection.
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. Centrifuge and aliquot 1 mL of serum into plastic vial.
2. Send specimen frozen.
Useful For
Screening for bile acid malabsorption in patients with irritable bowel syndrome with diarrhea
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
7AC4, Bile Acid Synthesis, SSpecimen Type
SerumSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Frozen (preferred) | 90 days | |
| Refrigerated | 72 hours | ||
| Ambient | 24 hours |
Reference Values
≥18 years: 2.5-63.2 ng/mL
Reference values have not been established for patients who are <18 years of age.
Day(s) Performed
Monday, Thursday
Report Available
5 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
82542
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| 7AC4 | 7AC4, Bile Acid Synthesis, S | 94866-1 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 65504 | 7AC4, Bile Acid Synthesis, S | 94866-1 |
Forms
If not ordering electronically, complete, print, and send Gastroenterology and Hepatology Test Request (T728) with the specimen
Testing Algorithm
For more information see Ordering Guide: Bile Acid-Associated Tests.