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Test ID ACMFS Acetylcholine Receptor Modulating Antibody, Flow Cytometry Assay, Serum


Ordering Guidance


Typically, physicians will order acetylcholine receptor (AChR) binding, blocking, and modulating antibodies. Mayo Clinic Laboratories' (MCL) tests are not named in that manner; instead these are offered as myasthenia gravis (MG) evaluations. MGMR / Myasthenia Gravis Evaluation with MuSK Reflex, Serum is the testing of choice in most cases.

 

AChR blocking antibody testing is no longer offered individually as it offers no added-value to the diagnosis and management of MG.



Specimen Required


Only orderable as part of a profile. For more information see:

MGLE / Myasthenia Gravis (MG)/Lambert-Eaton Myasthenic Syndrome (LEMS) Evaluation, Serum

MGMR / Myasthenia Gravis Evaluation with MuSK Reflex, Serum

PAVAL / Paraneoplastic, Autoantibody Evaluation, Serum

 

Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Specimen Volume: 1 mL


Useful For

Diagnosis for autoimmune myasthenia gravis (MG) in adults and children

 

Distinguishing autoimmune from congenital MG in adults and children or other acquired forms of neuromuscular junction transmission disorders.

 

This test is a qualitative assay and should not be used for monitoring purposes.

Method Name

Only orderable as part of a profile. For more information see:

MGLE / Myasthenia Gravis (MG)/Lambert-Eaton Myasthenic Syndrome (LEMS) Evaluation, Serum

MGMR / Myasthenia Gravis Evaluation with MuSK Reflex, Serum

PAVAL / Paraneoplastic, Autoantibody Evaluation, Serum

 

Flow Cytometry

Reporting Name

AChR Modulating Flow Cytometry, S

Specimen Type

Serum

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  72 hours

Reference Values

Only orderable as part of a profile. For more information see:

MGLE / Myasthenia Gravis (MG)/Lambert-Eaton Myasthenic Syndrome (LEMS) Evaluation, Serum

MGMR / Myasthenia Gravis Evaluation with MuSK Reflex, Serum

PAVAL / Paraneoplastic, Autoantibody Evaluation, Serum

 

Negative

Day(s) Performed

Monday, Wednesday, Saturday

Report Available

5 to 8 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

86255

LOINC Code Information

Test ID Test Order Name Order LOINC Value
ACMFS AChR Modulating Flow Cytometry, S In Process

 

Result ID Test Result Name Result LOINC Value
610029 AChR Modulating Flow Cytometry, S In Process

NY State Approved

No