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Test ID AFPSF Alpha-Fetoprotein (AFP), Spinal Fluid

Useful For

An adjunct in the diagnosis of central nervous system (CNS) germinomas and meningeal carcinomatosis

 

Evaluating germ-cell tumors, including testicular cancer metastatic to the CNS in conjunction with beta-human chorionic gonadotropin measurement(1)

 

An adjunct in distinguishing between suprasellar dysgerminomas and craniopharyngiomas

 

A supplement to cerebrospinal fluid cytologic analysis

Method Name

Immunoenzymatic Assay

Reporting Name

Alpha-Fetoprotein, CSF

Specimen Type

CSF


Specimen Required


Container/Tube: Sterile vial

Specimen Volume: 1 mL


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
CSF Frozen (preferred) 7 days
  Refrigerated  7 days

Reference Values

<1.5 ng/mL

Values for alpha-fetoprotein in cerebrospinal fluid have not been formally established for newborns and infants. The available literature indicates that by 2 months of age, levels comparable to adults should be reached.(Ann Clin Biochem 2005;42:24-29)

Day(s) and Time(s) Performed

Monday through Friday; 5 a.m.-12 a.m., Saturday; 6 a.m.-6 p.m.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

86316

LOINC Code Information

Test ID Test Order Name Order LOINC Value
AFPSF Alpha-Fetoprotein, CSF 1833-3

 

Result ID Test Result Name Result LOINC Value
AFSF Alpha-Fetoprotein, CSF 1833-3

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

NY State Approved

Yes