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Test ID BAP Bone Alkaline Phosphatase, Serum

Useful For

Diagnosis and assessment of severity of metabolic bone disease including Paget disease, osteomalacia, and other states of high bone turnover


Monitoring efficacy of antiresorptive therapies including postmenopausal osteoporosis treatment


The assay is not intended as a screening test for osteoporosis.


Measurements of bone turnover markers are not useful for the diagnosis of osteoporosis; diagnosis of osteoporosis should be made based on bone density.

Method Name

Immunoenzymatic Assay

Reporting Name

Bone Alkaline Phosphatase, S

Specimen Type


Specimen Required

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.6 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial.

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  90 days
  Ambient  7 days

Reference Values


<2 years: 25-221 mcg/L

2-9 years: 27-148 mcg/L

10-13 years: 35-169 mcg/L

14-17 years: 13-111 mcg/L

Adults: ≤20 mcg/L



<2 years: 28-187 mcg/L

2-9 years: 31-152 mcg/L

10-13 years: 19-177 mcg/L

14-17 years: 7-41 mcg/L


Premenopausal: ≤14 mcg/L

Postmenopausal: ≤22 mcg/L

Day(s) Performed

Monday through Saturday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
BAP Bone Alkaline Phosphatase, S 17838-4


Result ID Test Result Name Result LOINC Value
BAP Bone Alkaline Phosphatase, S 17838-4

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

Report Available

2 to 3 days

NY State Approved