Sign in →

Test ID BHYD Beta-Hydroxybutyrate, Serum

Useful For

Monitoring therapy for diabetic ketoacidosis


Investigating the differential diagnosis of any patient presenting to the emergency room with hypoglycemia, acidosis, suspected alcohol ingestion, or an unexplained increase in the anion gap


In pediatric patients, the presence or absence of ketonemia/uria is an essential component in the differential diagnosis of inborn errors of metabolism


Serum beta-hydroxybutyrate is a key parameter monitored during controlled 24-hour fasts

Method Name

Photometric, B-Hydroxybutyrate Dehydrogenase (B-HBDH)

Reporting Name

Beta-Hydroxybutyrate, S

Specimen Type


Specimen Required

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Serum gel tubes should be centrifuged within 2 hours of collection.

2. Red-top tubes should be centrifuged and aliquoted within 2 hours of collection.

Specimen Minimum Volume

0.25 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Frozen (preferred) 7 days
  Refrigerated  7 days

Reference Values

<0.4 mmol/L

Day(s) Performed

Monday through Sunday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
BHYD Beta-Hydroxybutyrate, S 6873-4


Result ID Test Result Name Result LOINC Value
BHYD Beta-Hydroxybutyrate, S 6873-4

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

Report Available

Same day/1 to 2 days

NY State Approved