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Test ID C5FX C5 Complement, Functional, Serum

Useful For

Diagnosis of C5 deficiency

 

Investigation of a patient with an undetectable total complement (CH50) level

Method Name

Automated Liposome Lysis Assay

Reporting Name

C5 Complement, Functional, S

Specimen Type

Serum Red


Advisory Information


The total complement (CH50) assay (COM / Complement, Total, Serum) should be used as a screen for suspected complement deficiencies before ordering individual complement component assays. A deficiency of an individual component of the complement cascade will result in an undetectable total complement level.

Specimen Required


Patient Preparation: Fasting preferred

Supplies: Aliquot Tube, 5 mL (T465)

Collection Container/Tube: Red top

Submission Container/Tube: Plastic, 5 mL tube

Specimen Volume: 1 mL

Collection Instructions:

1. Immediately after specimen collection, place the tube on wet ice.

2. Centrifuge and separate serum from clot.

3. Immediately freeze specimen.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Frozen 14 days

Reference Values

29-53 U/mL

Day(s) and Time(s) Performed

Monday through Saturday; Continuously with a 3 p.m. cutoff

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

86161

LOINC Code Information

Test ID Test Order Name Order LOINC Value
C5FX C5 Complement, Functional, S 60472-8

 

Result ID Test Result Name Result LOINC Value
C5FX C5 Complement, Functional, S 60472-8

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.