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Test ID CDH1Z CDH1 Gene, Full Gene Analysis, Varies

Useful For

Confirmation of suspected clinical diagnosis of hereditary diffuse gastric cancer

 

Identification of familial CDH1 variant to allow for predictive testing in family members

 

Predictive testing of an asymptomatic child is not recommended.

Additional Tests

Test ID Reporting Name Available Separately Always Performed
COLAB Hereditary Colon Cancer CGH Array Yes, (order FMTT) Yes

Testing Algorithm

When this test is ordered, array comparative genomic hybridization will always be performed at an additional charge.

Method Name

Polymerase Chain Reaction (PCR) Amplification followed by DNA Sequencing

COLAB: Gene Dosage Analysis by Array Comparative Genomic Hybridization (aCGH)

Reporting Name

CDH1 Gene, Full Gene Analysis

Specimen Type

Varies


Shipping Instructions


Specimen preferred to arrive within 96 hours of collection.



Specimen Required


Patient Preparation: A previous bone marrow transplant from an allogenic donor will interfere with testing. Call 800-533-1710 for instructions for testing patients who have received a bone marrow transplant.

Specimen Type: Whole blood

Container/Tube:

Preferred: Lavender top (EDTA) or yellow top (ACD)

Acceptable: Any anticoagulant

Specimen Volume: 3 mL

Collection Instructions:

1. Invert several times to mix blood.

2. Send specimen in original tube.


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Varies Ambient (preferred)
  Frozen 
  Refrigerated 

Reference Values

An interpretive report will be provided.

Day(s) Performed

Varies

Report Available

14 to 20 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

81406

Hereditary Colon Cancer CGH Array, additional test

81228

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CDH1Z CDH1 Gene, Full Gene Analysis 94240-9

 

Result ID Test Result Name Result LOINC Value
52487 Result Summary 50397-9
52488 Result 82939-0
52489 Interpretation 69047-9
52490 Additional Information 48767-8
52491 Specimen 31208-2
52492 Source 31208-2
52494 Array Billed? No LOINC Needed
52495 Released By 18771-6

NY State Approved

Yes

Forms

1. New York Clients-Informed consent is required. Document on the request form or electronic order that a copy is on file. The following documents are available in Special Instructions:

-Informed Consent for Genetic Testing (T576)

-Informed Consent for Genetic Testing-Spanish (T826)

2. Molecular Genetics: Inherited Cancer Syndromes Patient Information (T519) in Special Instructions