Test ID CEBPA CEBPA Mutations, Gene Sequencing, Varies
Useful For
Initial evaluation of acute myeloid leukemia, both for assigning an appropriate diagnostic subclassification and as an aid for determining prognosis
Special Instructions
Method Name
Mutation Detection in DNA Using Sanger Sequencing
Reporting Name
CEBPA Mutations, SequencingSpecimen Type
VariesAdvisory Information
This test is intended for use at the time of diagnosis and not for disease monitoring.
Shipping Instructions
Specimen must arrive within 7 days (168 hours) of collection.
Necessary Information
The following information is required:
1. Pertinent clinical history
2. Clinical or morphologic suspicion
3. Date of collection
4. Specimen source
Specimen Required
Submit only 1 of the following specimens:
Specimen Type: Peripheral Blood
Container/Tube: EDTA (lavender top or ACD (yellow top)
Specimen Volume: 3 mL
Collection Instructions:
1. Invert several times to mix blood.
2. Send specimen in original tube.
3. Label specimen as blood.
Specimen Stability: Ambient (preferred)/Refrigerate
Specimen Type: Bone marrow
Container/Tube: EDTA (lavender top) or ACD (yellow top)
Specimen Volume: 2 mL
Collection Instructions:
1. Invert several times to mix bone marrow.
2. Send specimen in original tube.
3. Label specimen as bone marrow.
Specimen Stability: Ambient (preferred)/Refrigerate
Specimen Type: Extracted DNA from blood or bone marrow
Container/Tube: 1.5- to 2-mL tube
Specimen Volume: Entire specimen
Collection Instructions: Label specimen as extracted DNA from blood or bone marrow and provide indication of volume and concentration of the DNA.
Specimen Stability: Frozen (preferred)/Refrigerate/Ambient
Specimen Minimum Volume
1 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Varies | Varies | 7 days |
Reference Values
An interpretive report will be provided
Day(s) and Time(s) Performed
Monday through Friday
Performing Laboratory

CPT Code Information
81218-CEBPA (CCAAT/enhancer binding protein [C/EBP], alpha) (eg, acute myeloid leukemia), gene analysis, full gene sequence
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
CEBPA | CEBPA Mutations, Sequencing | 75009-1 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
MP019 | Specimen: | 31208-2 |
34634 | Final Diagnosis: | 34574-4 |
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.NY State Approved
YesForms
1. Hematopathology Patient Information (T676) in Special Instructions
2. If not ordering electronically, complete, print, and send a Hematopathology/Cytogenetics Test Request (T726) with the specimen.