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Test ID CMAPT Chromosomal Microarray, Tumor, Formalin-Fixed Paraffin-Embedded

Useful For

Genomic characterization of tumor for copy number imbalances and loss of heterozygosity

 

Assisting in the diagnosis and classification of malignant neoplasms

 

Evaluating the prognosis for patients with malignant tumors

Testing Algorithm

This test does not include a pathology consult. If a pathology consultation is requested, PATHC / Pathology Consultation should be ordered and the appropriate FISH test will be ordered and performed at an additional charge.

 

Hematoxylin and eosin stain review of the paraffin-embedded sample is performed to identify the area of invasive tumor prior to DNA extraction and microarray analysis. If additional FISH testing is requested, it will be performed at an additional charge.

 

If a fresh specimen or specimen in fixative is submitted, ANPAT / Anatomic Pathology Consultation, Wet Tissue will be added by the laboratory, at an additional charge, to facilitate the performance of this test.   

 

See Aggressive B-cell Lymphoma Diagnostic Algorithm in Special Instructions.

Method Name

Chromosomal Microarray (CMA) Using Applied Biosystems (Affymetrix) Oncoscan 

Reporting Name

Chromosomal Microarray, Tumor, FFPE

Specimen Type

Varies


Advisory Information


 



Additional Testing Requirements


If a fresh specimen or specimen in fixative is submitted, ANPAT / Anatomic Pathology Consultation, Wet Tissue will be added by the laboratory, at an additional charge, to facilitate the performance of this test.



Necessary Information


A reason for referral and pathology report are required in order for testing to be performed. Send information with specimen. Acceptable pathology reports include working drafts, preliminary pathology or surgical pathology reports.



Specimen Required


Submit only 1 of the following specimens:

 

Specimen Type: Tissue

Container/Tube: Formalin-fixed, paraffin-embedded tumor tissue block

 

Specimen Type: Slides

Specimen Volume: 10 Consecutive, unstained, 5-micron-thick sections placed on positively charged slides and 1 hematoxylin and eosin-stained slide


Specimen Minimum Volume

See Specimen Required

Specimen Stability Information

Specimen Type Temperature Time Special Container
Varies Ambient (preferred)
  Refrigerated 

Reference Values

An interpretive report will be provided.

Day(s) and Time(s) Performed

Specimens are processed Monday through Sunday.

Results reported Monday through Friday, 8 a.m.-5 p.m.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

81277

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CMAPT Chromosomal Microarray, Tumor, FFPE 94087-4

 

Result ID Test Result Name Result LOINC Value
54735 Result Summary 50397-9
54736 Result 62356-1
54737 Nomenclature 62378-5
54738 Interpretation 69965-2
CG908 Reason for Referral 42349-1
54744 Specimen 31208-2
54739 Source 31208-2
54740 Tissue ID 80398-1
54741 Method 49549-9
53425 Additional Information 48767-8
54742 Released By 18771-6

NY State Approved

Yes