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Test ID CRSY Chromium, Synovial Fluid


Specimen Required


Patient Preparation: High concentrations of gadolinium and iodine are known to potentially interfere with most inductively coupled plasma mass spectrometry-based metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for at least 96 hours.

Supplies:

-Metal Free EDTA 3 mL Tube (T989)

-Metal Free B-D Tube (EDTA), 6 mL (T183)

Container/Tube:

Preferred: Royal blue-top BD vacutainer with EDTA blood collection tube (3 mL) (BD catalog no. 367777) (T989)

Acceptable: Royal blue-top BD Vacutainer Plus with EDTA blood collection tube (6 mL) (BD catalog no. 368381) (T183)

Specimen Volume: 1 mL

Collection Instructions: See Metals Analysis Specimen Collection and Transport for complete instructions.

Additional Information: Chromium is present in the black rubber plunger seals found in most disposable syringes. As a result, synovial fluid should not be collected in these devices as contamination may occur.


Useful For

Monitoring metallic prosthetic implant wear and local tissue destruction in failed hip arthroplasty constructs

 

This test is not useful for assessment of potential chromium toxicity.

Method Name

Inductively Coupled Plasma Mass Spectrometry (ICP-MS)

Reporting Name

Chromium, Synovial Fl

Specimen Type

Synovial Fluid

Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time
Synovial Fluid Refrigerated (preferred) 90 days
  Ambient  90 days
  Frozen  90 days

Reference Values

0-17 years: Not established

≥18 years: <16.9 ng/mL

Day(s) Performed

Friday

Report Available

2 to 8 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

82495

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CRSY Chromium, Synovial Fl 95526-0

 

Result ID Test Result Name Result LOINC Value
606353 Chromium, Synovial Fl 95526-0