Test ID CRSY Chromium, Synovial Fluid
Specimen Required
Patient Preparation: High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for at least 96 hours
Supplies: Metal Free B-D Tube (EDTA), 6 mL (T183)
Container/Tube: Royal blue top (metal-free EDTA)
Specimen Volume: 1 mL
Collection Instructions: See Trace Metals Analysis Specimen Collection and Transport in Special Instructions for complete instructions.
Additional Information: Chromium is present in the black rubber plunger seals found in most disposable syringes. As a result, synovial fluid should not be collected in these devices as contamination may occur.
Useful For
Monitoring metallic prosthetic implant wear and local tissue destruction in failed hip arthroplasty constructs
This test is not useful for assessment of potential chromium toxicity.
Special Instructions
Method Name
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)
Reporting Name
Chromium, Synovial FlSpecimen Type
Synovial FluidSpecimen Minimum Volume
0.4 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Synovial Fluid | Refrigerated (preferred) | 90 days | |
Ambient | 90 days | ||
Frozen | 90 days |
Reference Values
 0-17 years: Not established
≥18 years: <17.1 ng/mL
Day(s) and Time(s) Performed
Thursday; 8 a.m.
Performing Laboratory

Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
82495
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
CRSY | Chromium, Synovial Fl | 95526-0 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
606353 | Chromium, Synovial Fl | 95526-0 |