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Test ID CXCFX MYD88 Reflex to CXCR4 Mutation Detection, Varies


Specimen Required


Only orderable as a reflex. For more information, see LPLFX / Reflexive Testing of MYD88 and CXCR4

 

Submit only 1 of the following specimens:

 

Specimen Type: Peripheral blood

Container/Tube: EDTA (lavender top) or ACD solution B (yellow top

Specimen Volume: 3 mL

Specimen Stability: Ambient (preferred)/Refrigerated

Collection Instructions:

1. Invert several times to mix blood

2. Send specimen in original tube

3. Label specimen as blood

 

Specimen Type: Bone marrow

Container/Tube: EDTA (lavender top) or ACD solution B (yellow top)

Specimen Volume: 2 mL

Specimen Stability: Ambient (preferred)/Refrigerated

Collection Instructions:

1. Invert several times to mix bone marrow

2. Send specimen in original tube

3. Label specimen as bone marrow

 

Specimen Type: Extracted DNA

Container/Tube: 1.5- to 2-mL tube with indication of volume and concentration of the DNA

Specimen Volume: Entire specimen

Specimen Stability: Frozen (preferred)/Refrigerated/Ambient

Collection Instructions: Label specimen as extracted DNA and list specimen source. Include indication of volume and concentration of the DNA.

 

Specimen Type: Paraffin-embedded tissue

Container/Tube: Paraffin block

Specimen Stability: Ambient

 

Specimen Type: Paraffin-embedded bone marrow aspirate clot

Container/Tube: Paraffin block

Specimen Stability: Ambient


Useful For

The prognostication and clinical management of lymphoplasmacytic lymphoma/Waldenstrom macroglobulinemia

Method Name

Only orderable as a reflex. For more information, see LPLFX / Reflexive Testing of MYD88 and CXCR4.

Reporting Name

CXCR4, Gene Mutation, Reflex

Specimen Type

Varies

Specimen Minimum Volume

Blood, Bone Marrow: 1 mL
Extracted DNA: 20 mcL with a concentration of at least 10 nanograms per mcL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Varies Varies 10 days

Reference Values

Only orderable as a reflex. For more information, see LPLFX / Reflexive Testing of MYD88 and CXCR4

 

An interpretive report will be provided

Day(s) and Time(s) Performed

Monday through Friday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

81479-Unlisted molecular pathology procedure

NY State Approved

No