Test ID CXCFX MYD88 Reflex to CXCR4 Mutation Detection, Varies
Specimen Required
Only orderable as a reflex. For more information, see LPLFX / Reflexive Testing of MYD88 and CXCR4
Submit only 1 of the following specimens:
Specimen Type: Peripheral blood
Container/Tube: EDTA (lavender top) or ACD solution B (yellow top
Specimen Volume: 3 mL
Specimen Stability: Ambient (preferred)/Refrigerated
Collection Instructions:
1. Invert several times to mix blood
2. Send specimen in original tube
3. Label specimen as blood
Specimen Type: Bone marrow
Container/Tube: EDTA (lavender top) or ACD solution B (yellow top)
Specimen Volume: 2 mL
Specimen Stability: Ambient (preferred)/Refrigerated
Collection Instructions:
1. Invert several times to mix bone marrow
2. Send specimen in original tube
3. Label specimen as bone marrow
Specimen Type: Extracted DNA
Container/Tube: 1.5- to 2-mL tube with indication of volume and concentration of the DNA
Specimen Volume: Entire specimen
Specimen Stability: Frozen (preferred)/Refrigerated/Ambient
Collection Instructions: Label specimen as extracted DNA and list specimen source. Include indication of volume and concentration of the DNA.
Specimen Type: Paraffin-embedded tissue
Container/Tube: Paraffin block
Specimen Stability: Ambient
Specimen Type: Paraffin-embedded bone marrow aspirate clot
Container/Tube: Paraffin block
Specimen Stability: Ambient
Useful For
The prognostication and clinical management of lymphoplasmacytic lymphoma/Waldenstrom macroglobulinemia
Special Instructions
Method Name
Only orderable as a reflex. For more information, see LPLFX / Reflexive Testing of MYD88 and CXCR4.
Reporting Name
CXCR4, Gene Mutation, ReflexSpecimen Type
VariesSpecimen Minimum Volume
Blood, Bone Marrow: 1 mL
Extracted DNA: 20 mcL with a
concentration of at least 10 nanograms per mcL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Varies | Varies | 10 days |
Reference Values
Only orderable as a reflex. For more information, see LPLFX / Reflexive Testing of MYD88 and CXCR4
An interpretive report will be provided
Day(s) and Time(s) Performed
Monday through Friday
Performing Laboratory

Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
81479-Unlisted molecular pathology procedure