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HelpTest ID DENGS Dengue Virus, Molecular Detection, PCR, Serum
Advisory Information
The presence of dengue virus nucleic acid in serum overlaps with the presence of dengue virus nonstructural protein 1 (NS1) antigen (DNSAG / Dengue Virus NS1 Antigen, Serum). Patients with a history of symptoms for more than 1 week may be negative by molecular tests (ie, real-time PCR) and may require serologic testing (DENVP / Dengue Virus Antibody/Antigen Panel, Serum) to confirm the diagnosis of dengue virus infection.
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container: Sterile container
Specimen Volume: 0.5 mL
Collection Instructions:
1. Collect whole blood in a serum gel tube.
2. Centrifuge and aliquot the serum into a sterile container within 6 hours of collection.
3. Label specimen as serum.
Useful For
Aiding in the diagnosis of acute infection caused by dengue virus
Highlights
Detection of dengue virus nucleic acid in serum is suggestive of recent exposure and acute infection with dengue virus.
The presence of dengue virus nucleic acid in serum can be used as a marker for acute-phase infection. Patients with a history of symptoms for more than 1 week may be negative by molecular tests (ie, real-time PCR) and may require serologic testing to confirm the diagnosis of dengue virus infection.
Testing Algorithm
See Mosquito-borne Disease Laboratory Testing in Special Instructions.
Special Instructions
Method Name
Real-Time Polymerase Chain Reaction (PCR)
Reporting Name
Dengue Virus, PCR, SerumSpecimen Type
SerumSpecimen Minimum Volume
0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 7 days | |
| Frozen | 7 days |
Reference Values
Negative
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
87798
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| DENGS | Dengue Virus, PCR, Serum | 94427-2 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 606372 | Dengue Virus, PCR, Serum | 94427-2 |