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Test ID DIS2 HLA Class II Molecular Typing Disease Association, Whole Blood

Useful For

Determining human leukocyte antigens (HLA) class II antigens on specimens for disease associations

Method Name

Polymerase Chain Reaction (PCR)/Sequence-Specific Oligonucleotide Probes (SSO)

Reporting Name

HLA ClassII Mol Typing DiseaseAssoc

Specimen Type

Whole Blood ACD-B

Specimen Required

Container/Tube: Yellow top (ACD solution B)

Specimen Volume: 6 mL

Collection Instructions: Do not transfer blood to other containers.

Additional Information: Specimen acceptability is based on extracted DNA concentration and not sample age.

Specimen Minimum Volume

3 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Whole Blood ACD-B Refrigerated (preferred)

Reference Values

Not applicable

Day(s) and Time(s) Performed

Monday through Friday; 7:30 a.m.-5 p.m.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

81375-HLA Class II typing, low resolution (eg, antigen equivalents); HLA-DRB1/3/4/5 and -DQB1

LOINC Code Information

Test ID Test Order Name Order LOINC Value
DIS2 HLA ClassII Mol Typing DiseaseAssoc In Process


Result ID Test Result Name Result LOINC Value
DR DR Locus Serology 21341-3
DR1 DRB1 Locus Molecular 57298-2
DRW DRw Locus Serology 13304-1
DRB3M DRB3 Locus Molecular 59022-4
DRB4M DRB4 Locus Molecular 59021-6
DRB5M DRB5 Locus Molecular 59020-8
DQ DQ Locus Serology 13305-8
DQ2 DQA1 Locus Molecular 44728-4
DQ1 DQB1 Locus Molecular 43291-4
DP2 DPA1 Locus Molecular 59018-2
DP3 DPB1 Locus Molecular 59017-4

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

NY State Approved



If not ordering electronically, complete, print, and send a Hematopathology/Cytogenetics Test Request (T726) with the specimen.