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HelpTest ID DOCS 11-Deoxycorticosterone, Serum
Useful For
Diagnosis of suspected 11-hydroxylase deficiency, including the differential diagnosis of 11-beta-hydroxylase 1 (CYP11B1) versus 11-beta-hydroxylase 2 (CYP11B2) deficiency
Diagnosis of glucocorticoid-responsive hyperaldosteronism
Evaluating congenital adrenal hyperplasia newborn screen-positive children, when elevations of 17-hydroxyprogesterone are only moderate, suggesting possible 11-hydroxylase deficiency
Testing Algorithm
For more information see Steroid Pathways.
Special Instructions
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
11-Deoxycorticosterone, SSpecimen Type
SerumSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions:
1. Morning (8 a.m.) specimen is preferred.
2. Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.4 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 21 days | |
| Frozen | 21 days | ||
| Ambient | 7 days |
Reference Values
≤18 years: <30 ng/dL
>18 years: <10 ng/dL
Day(s) Performed
Tuesday
Report Available
3 to 10 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
82633
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| DOCS | 11-Deoxycorticosterone, S | 1656-8 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 46922 | 11-Deoxycorticosterone, S | 1656-8 |