Test ID EDOXA Edoxaban, Anti-Xa, Plasma
Advisory Information
This assay is not indicated for monitoring low-molecular-weight heparin (LMWH) or unfractionated heparin (UFH) concentrations. The presence of UFH and LMWH will cause the edoxaban anti-Xa level to be falsely elevated.
Necessary Information
If priority specimen, mark request form, give reason, and request a call-back.
Specimen Required
Specimen Type: Platelet-poor plasma
Collection Container/Tube: Light-blue top (citrate)
Submission Container/Tube: Polypropylene vial
Specimen Volume: 1 mL
Collection Instructions:
1. Specimen should be drawn 1 to 3 hours (peak) after a dose or just prior (trough) to the next dose for edoxaban concentrations.
2. For complete instructions, see Coagulation Guidelines for Specimen Handling and Processing in Special Instructions.
3. Centrifuge, transfer all plasma into a plastic vial, and centrifuge plasma again.
4. Aliquot plasma into a plastic vial leaving 0.25 mL in the bottom of centrifuged vial.
5. Freeze plasma immediately (no longer than 4 hours after collection) at -20° C or, ideally, ≤-40° C.
Additional Information:
1. A double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results.
2. Each coagulation assay requested should have its own vial.
Useful For
Measuring edoxaban concentration in plasma
This test is not useful for monitoring low-molecular-weight heparin (LMWH) or unfractionated heparin (UFH) concentrations.
Special Instructions
Method Name
Chromogenic Assay
Reporting Name
Edoxaban, Anti-Xa, PSpecimen Type
Plasma Na CitSpecimen Minimum Volume
0.5 mL plasma
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Plasma Na Cit | Frozen | 42 days |
Reference Values
<10 ng/mL
Day(s) and Time(s) Performed
Monday through Friday
Performing Laboratory

Test Classification
This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
80299
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
EDOXA | Edoxaban, Anti-Xa, P | 95128-5 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
EDOX1 | Edoxaban, Anti-Xa, P | 95128-5 |
EDOX2 | Interpretation | 69049-5 |
EDOX3 | Cautions | 62364-5 |
NY State Approved
YesForms
If not ordering electronically, complete, print, and send a Coagulation Test Request (T753) with the specimen.