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Test ID FEC Iron and Total Iron-Binding Capacity, Serum

Useful For

Screening for chronic iron overload diseases, particularly hereditary hemochromatosis

Method Name

Immunoturbidimetric Assay

Reporting Name

Iron and Total Fe Binding Cap, S

Specimen Type


Necessary Information

Patient's age and sex are required.

Specimen Required

Patient Preparation:

1. Fasting (12 hours)

2. Iron-containing supplements should be avoided for 24 hours prior to draw.


Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 1 mL

Collection Instructions:

1. Draw blood before 12 noon (preferred).

2. Serum gel tubes should be centrifuged within 2 hours of collection.

3. Red-top tubes should be centrifuged and aliquoted within 2 hours of collection.

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 7 days
  Frozen  180 days

Reference Values


Males: 50-150 mcg/dL

Females: 35-145 mcg/dL



250-400 mcg/dL




Day(s) and Time(s) Performed

Monday through Saturday; Continuously

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information


83550-Iron-binding capacity

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FEC Iron and Total Fe Binding Cap, S 50190-8


Result ID Test Result Name Result LOINC Value
IRON Iron 2498-4
TIBC Total Iron Binding Capacity 2500-7
SAT Percent Saturation 2502-3

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

Testing Algorithm

See Hereditary Hemochromatosis Algorithm in Special Instructions.

NY State Approved



If not ordering electronically, complete, print, and send a Benign Hematology Test Request Form (T755) with the specimen.