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Test ID FFTRP Trofile Co-Receptor Tropism Assay

Useful For

To determine the co-receptor tropism (CCR5, CXCR4, or dual/mixed) of a patient's HIV-1 strain for selection of CCR5 co-receptor antagonist therapy, when a patient's HIV-1 viral load is ≥ 1,000 copies/mL. 

Method Name

CD4 cell culture assay for phenotypic recombinant-virus co-receptor tropism.

Reporting Name

Trofile Phenotypic Corecept Tropism

Specimen Type

Plasma EDTA

Specimen Required

Draw blood in either PPT (pearl top) or lavender-top (EDTA) tubes. Remove plasma from cells immediately, and transfer specimen to a screw-capped, plastic vial. Freeze 3 mL of PPT plasma or EDTA plasma immediately, send specimen frozen.



1.       Patient's most recent viral load

2.       Viral load collection date


Note:   1.  Intended to use only for patients with viral loads greater than or equal to 1000 copies/mL. For best results, viral loads should be confirmed within two weeks prior to submission for testing at Monogram.

           2. Patient samples submitted <30 days apart are considered duplicate and will be cancelled.

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma EDTA Frozen 14 days

Day(s) Performed

Monday through Friday

Performing Laboratory

Monogram Biosciences, Inc

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
FFTRP Trofile Phenotypic Corecept Tropism 57182-8


Result ID Test Result Name Result LOINC Value
Z1038 Tropotype Result 57182-8
Z1039 Note: Not Provided
Z1040 Activity of CCR5 antag anticipated? Not Provided

Report Available

18 to 23 days

NY State Approved