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Test ID FKEMS Ketamine and Metabolite Screen, Plasma


Specimen Required


***Must submit one specimen per order. Specimens cannot be shared between multiple orders.***

Specimen Type: Plasma

Collection Container/Tube: Lavender-top or pink top (EDTA)

Submission Container/Tube: Plastic vial

Specimen Volume: 3 mL

Collection Instructions:

1. Draw blood in an EDTA (lavender top or pink top) tube(s). Plasma gel tube is not acceptable.

2. Centrifuge and send 3 mL of plasma refrigerated in a preservative-free plastic vial.


Reflex Tests

Test ID Reporting Name Available Separately Always Performed
FKETC Ketamine and Metabolite Confirm, P No No

Testing Algorithm

Confirmation test, Ketamine and Metabolite Confirmation (FKETC), will be performed, if appropriate, at an additional charge.

Method Name

High Performance Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

Ketamine and Metabolite Screen, P

Specimen Type

Plasma EDTA

Specimen Minimum Volume

0.9 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma EDTA Refrigerated (preferred) 14 days
  Frozen  270 days
  Ambient  14 days

Reference Values

Reporting limit determined each analysis

 

Units: ng/mL

 

Norketamine: None Detected

The intravenous administration of 2 mg/kg of Ketamine followed by continuous infusion of 41 mcg/kg/minute produced an average steady-state plasma concentration of 2200 ng Ketamine/mL and an average peak Norketamine level of 1050 ng/mL which occurred near the end of the 3 hour infusion.

 

Ketamine: None Detected

Reported levels during anesthesia: 500-6500 ng/mL

Performing Laboratory

NMS Labs

Test Classification

This test was developed and its performance characteristics determined by NMS Labs. It has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

80307-Screen

80357-Confirmation, if appropriate

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FKEMS Ketamine and Metabolite Screen, P Not Provided

 

Result ID Test Result Name Result LOINC Value
Z6035 Norketamine Not Provided
Z6036 Ketamine 42922-5

Day(s) Performed

Monday through Sunday

Report Available

6-12 days