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Test ID FOPIA Opiates, Serum or Plasma, Quantitative

Method Name

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Reporting Name

Opiates, Serum or Plasma, Quant.

Specimen Type


Specimen Required

Submit only one of the following:



Draw blood in a gray top potassium oxalate/sodium fluoride, green (sodium heparin), lavender (EDTA) or pink (K2EDTA) tube(s). Spin down and send 1 mL of plasma refrigerated in a plastic vial.



Draw blood in a plain, red-top tube(s). Spin down and send 1 mL of serum refrigerated in a plastic vial.

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Varies Refrigerated (preferred) 14 days
  Ambient  7 days

Reference Values

Drugs covered: codeine, morphine, 6-acetylmorphine, hydrocodone, hydromorphone, oxycodone, and oxymorphone. All drugs covered and the non-glucuronidated (free) form.


Positive cutoff: 2 ng/mL


For medical purposes only; not valid for forensic use.


Day(s) Performed

Monday, Wednesday and Friday

Report Available

1 to 8 days

Performing Laboratory

ARUP Laboratories

Test Classification

This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

CPT Code Information

80361, 80365

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FOPIA Opiates, Serum or Plasma, Quant. 8217-2


Result ID Test Result Name Result LOINC Value
Z4427 6-acetylmorphine, S/P, Quant 12788-6
Z4428 Codeine, S/P, Quant 3506-3
Z4429 Morphine, S/P, Quant 3827-3
Z4430 Hydrocodone, S/P, Quant 3680-6
Z4431 Hydromorphone, S/P, Quant 3683-0
Z4432 Oxycodone, S/P, Quant 3893-5
Z4433 Oxymorphone, S/P, Quant 60467-8

NY State Approved