Test ID GAAW Acid Alpha-Glucosidase, Leukocytes
Shipping Instructions
For optimal isolation of leukocytes, it is recommended the specimen arrive refrigerate within 96 hours of collection to be stabilized. Collect specimen Monday through Thursday only and not the day before a holiday. Specimen should be collected and packaged as close to shipping time as possible.
Specimen Required
Container/Tube:
Preferred: Yellow top (ACD solution B)
Acceptable: Yellow top (ACD solution A) or lavender top (EDTA)
Specimen Volume: 6 mL
Collection Instructions: Send specimen in original tube. Do not transfer blood to other containers.
Forms
1. New York Clients-Informed consent is required. Document on the request form or electronic order that a copy is on file. The following documents are available in Special Instructions:
-Informed Consent for Genetic Testing (T576)
-Informed Consent for Genetic Testing-Spanish (T826)
2. Biochemical Genetics Patient Information (T602) in Special Instructions
Useful For
Diagnosis of Pompe disease
Genetics Test Information
This test provides diagnostic testing for individuals with decreased alpha-glucosidase activity on newborn screen or clinical signs and symptoms suspicious for Pompe disease.
Testing Algorithm
The following are available in Special Instructions:
-Newborn Screen Follow-up for Pompe Disease
-Newborn Screening Act Sheet Pompe Disease: Decreased Acid Alpha-Glucosidase
Special Instructions
Method Name
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Acid Alpha-Glucosidase, LeukocytesSpecimen Type
Whole Blood ACDSpecimen Minimum Volume
2 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Whole Blood ACD | Refrigerated (preferred) | 4 days | |
Ambient | 72 hours |
Reference Values
≥1.50 nmol/hour/mg protein
An interpretive report is provided.
Day(s) and Time(s) Performed
Specimens are processed Monday through Sunday.
Assay is performed: Varies
Performing Laboratory

Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
82657
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
GAAW | Acid Alpha-Glucosidase, Leukocytes | 24051-5 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
606267 | Acid Alpha-Glucosidase, Leukocytes | 24051-5 |
606268 | Interpretation | 59462-2 |
606269 | Reviewed By | 18771-6 |