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Test ID GD65C Glutamic Acid Decarboxylase (GAD65) Antibody Assay, Spinal Fluid

Useful For

Possible use in evaluating patients with autoimmune encephalitis, stiff-person syndrome, autoimmune ataxia, autoimmune epilepsy, and other acquired central nervous system disorders affecting gabaminergic neurotransmission

Method Name

Radioimmunoassay (RIA)

Reporting Name

GAD65 Ab Assay, CSF

Specimen Type

CSF


Ordering Guidance


This test should not be requested in patients who have recently received radioisotopes, therapeutically or diagnostically, because of potential assay interference. The specific waiting period before specimen collection will depend on the isotope administered, the dose given and the clearance rate in the individual patient. Specimens will be screened for radioactivity prior to analysis. Radioactive specimens received in the laboratory will be held one week and assayed if sufficiently decayed or canceled if radioactivity remains.



Specimen Required


Container/Tube: Sterile vial

Specimen Volume: 1.5 mL


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
CSF Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  72 hours

Reference Values

≤0.02 nmol/L

Reference values apply to all ages.

Day(s) Performed

Monday through Sunday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

86341

LOINC Code Information

Test ID Test Order Name Order LOINC Value
GD65C GAD65 Ab Assay, CSF 94359-7

 

Result ID Test Result Name Result LOINC Value
21702 GAD65 Ab Assay, CSF 94359-7

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

Report Available

3 to 6 days

NY State Approved

Yes

Forms

If not ordering electronically, complete, print, and send a Neurology Specialty Testing Client Test Request (T732) with the specimen.