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Test ID HBAG Hepatitis B Surface Antigen, Serum

Useful For

Diagnosis of acute, recent, or chronic hepatitis B infection

 

Determination of chronic hepatitis B infection status

 

This test is not offered as a screening or confirmatory test for blood donor specimens.

 

This test, by itself , is not useful during the "window period" of acute hepatitis B virus (HBV) infection (ie, after disappearance of hepatitis B surface antigen and prior to appearance of hepatitis B surface antibody ). Testing for acute HBV infection should also include hepatitis B core IgM antibody (anti-HBc IgM).

Method Name

Chemiluminescence Immunoassay

Reporting Name

HBs Antigen, S

Specimen Type

Serum SST


Ordering Guidance


This test is not intended for stand-alone prenatal screening for chronic hepatitis B in pregnant women.

For testing such patients, order HBAGP / Hepatitis B Surface Antigen Prenatal, Serum.

 

This test is not intended for testing cadaver or grossly hemolyzed specimens. For testing such patients, order HBGCD / Hepatitis B Surface Antigen for Cadaveric or Hemolyzed Specimens, Serum, which is FDA-approved for testing on these sources.



Additional Testing Requirements


Testing for acute hepatitis B virus infection should also include HBIM / Hepatitis B Core Antibody, IgM, Serum, as during the acute HBV infection "window period", Hepatitis B surface (HBs) antigen and HBs antibody may not be detected.



Necessary Information


1. Date of collection is required.

2. Indicate if specimens are from autopsy/cadaver or hemolyzed sources so that the proper FDA-licensed assay can be performed.



Specimen Required


Collection Container/Tube: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL

Collection Instructions: 

1. Centrifuge blood collection tube per collection tube manufacturer's instructions (eg, centrifuge and aliquot within 2 hours of collection for BD Vacutainer tubes).

2. Transfer serum into aliquot tube.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum SST Frozen (preferred) 28 days
  Refrigerated  7 days
  Ambient  24 hours

Reference Values

Negative

See Viral Hepatitis Serologic Profiles in Special Instructions.

Day(s) Performed

Monday through Saturday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

87340

87341 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
HBAG HBs Antigen, S 5196-1

 

Result ID Test Result Name Result LOINC Value
H_BAG HBs Antigen, S 5196-1

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
HBGNT HBs Antigen Confirmation, S No No

Testing Algorithm

If hepatitis B surface antigen (HBsAg) screen is reactive with signal-to-cutoff (S/CO) ratio in the range of 1.00 to 100.0 then HBsAg confirmation will be performed at an additional charge.

 

See the following in Special Instructions:

-HBV Infection-Diagnostic Approach and Management Algorithm

-HBV Infection-Monitoring Before and After Liver Transplantation

Report Available

Same day/1 to 3 days

NY State Approved

Yes

Forms

If not ordering electronically, complete, print, and send a Gastroenterology and Hepatology Client Test Request (T728) with the specimen.