Sign in →

Test ID HCQ Hydroxychloroquine, Serum

Useful For

Monitoring serum hydroxychloroquine concentrations, assessing compliance, and adjusting dosage in patients

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

Hydroxychloroquine, S

Specimen Type

Serum Red

Specimen Required

Collection Container/Tube: Red top (gel tubes/SST are not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Collect specimen immediately before next scheduled dose.

2. Centrifuge and aliquot serum into plastic vial within 2 hours of collection.

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Red Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  21 days

Reference Values

For suppressive treatment of malaria, suggested plasma or serum concentrations should be >10 ng/mL.


For systemic lupus erythematosus, proposed serum target concentrations should be ≥500 ng/mL.

Report Available

3 to 7 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
HCQ Hydroxychloroquine, S 3684-8


Result ID Test Result Name Result LOINC Value
64947 Hydroxychloroquine, S 3684-8

NY State Approved


Day(s) Performed

Sunday, Tuesday, Thursday


If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.