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Test ID HICBL Histoplasma/Blastomyces Panel, Spinal Fluid

Specimen Required

Container/Tube: Sterile vial

Specimen Volume: 1.5 mL


If not ordering electronically, complete, print, and send a Microbiology Test Request (T732) with the specimen.

Useful For

Aiding in the diagnosis of Histoplasma meningitis


Detecting antibodies in patients having blastomycosis

Profile Information

Test ID Reporting Name Available Separately Always Performed
CHIST Histoplasma Ab, CSF Yes Yes
CBL Blastomyces Ab Immunodiffusion, CSF Yes Yes

Method Name

CHIST: Complement Fixation (CF)/Immunodiffusion

CBL: Immunodiffusion

Reporting Name

Histoplasma/Blastomyces Panel, CSF

Specimen Type


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
CSF Refrigerated (preferred) 14 days
  Frozen  14 days

Reference Values

Histoplasma ANTIBODY

Mycelial by complement fixation: Negative

Yeast by complement fixation: Negative

Antibody by immunodiffusion: Negative




Day(s) Performed

Monday through Friday

Report Available

3 to 6 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved or is exempt by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86698 x 3-Histoplasma Antibody, CSF

86612-Blastomyces Antibody, CSF

LOINC Code Information

Test ID Test Order Name Order LOINC Value
HICBL Histoplasma/Blastomyces Panel, CSF 91683-3


Result ID Test Result Name Result LOINC Value
15134 Blastomyces Immunodiffusion (CSF) 51741-7
15118 Histoplasma Mycelial (CSF) 27220-3
15119 Histoplasma Yeast (CSF) 27209-6
15120 Histoplasma Immunodiffusion (CSF) 91682-5

NY State Approved


Testing Algorithm

See Meningitis/Encephalitis Panel Algorithm in Special Instructions.