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HelpTest ID HIV2L HIV-2 Antibody Confirmation, Serum
Useful For
Confirmation of the presence of HIV-2 antibodies in patients with repeatedly reactive combined HIV-1 and HIV-2 antibody or HIV-2 antibody-only screening test results
Diagnosis of HIV-2 infection
Special Instructions
Method Name
Rapid Immunochromatographic Assay
Reporting Name
HIV-2 Ab Confirmation, SSpecimen Type
SerumOrdering Guidance
This confirmatory assay should be ordered only on specimens that are repeatedly reactive by HIV-2 antibody screening immunoassay.
Screening, supplemental, or confirmatory serologic tests for HIV-2 antibodies cannot distinguish between active HIV-2 infection and passive transfer of maternal HIV-2 antibodies in infants during the postnatal period (up to 2 years). Diagnosis of HIV-2 infection in newborns and infants of less than 2 years old should be made by consistently positive nucleic acid test results, such as the presence of HIV-2 DNA/RNA (FHV2Q / HIV-2 DNA/RNA Qualitative Real-Time PCR).
New York State clients: This test should not be requested for maternal/newborn HIV screening on specimens originating in New York State, due to state regulatory requirements for expedited result reporting.
Necessary Information
Date of collection is required.
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions:
1. Centrifuge blood collection tube per collection tube manufacturer's instructions (eg, centrifuge and aliquot within 2 hours of collection for BD Vacutainer tubes).
2. Aliquot serum into plastic vial.
Specimen Minimum Volume
0.2 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Frozen (preferred) | 30 days | |
| Refrigerated | 14 days | ||
| Ambient | 48 hours |
Reference Values
Negative
Day(s) Performed
Monday through Friday
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
86689
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| HIV2L | HIV-2 Ab Confirmation, S | 81641-3 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 61785 | HIV-2 Ab Confirmation, S | 81641-3 |
Test Classification
This test has been cleared, approved or is exempt by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.Testing Algorithm
The following algorithms are available in Special Instructions:
-HIV-2 Testing Algorithm: Screening (Nonsymptomatic) and Diagnostic (Symptomatic)