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Test ID HIV2L HIV-2 Antibody Confirmation, Serum

Useful For

Confirmation of the presence of HIV-2 antibodies in patients with repeatedly reactive combined HIV-1 and HIV-2 antibody or HIV-2 antibody-only screening test results


Diagnosis of HIV-2 infection

Method Name

Rapid Immunochromatographic Assay

Reporting Name

HIV-2 Ab Confirmation, S

Specimen Type


Ordering Guidance

This confirmatory assay should be ordered only on specimens that are repeatedly reactive by HIV-2 antibody screening immunoassay.


Screening, supplemental, or confirmatory serologic tests for HIV-2 antibodies cannot distinguish between active HIV-2 infection and passive transfer of maternal HIV-2 antibodies in infants during the postnatal period (up to 2 years). Diagnosis of HIV-2 infection in newborns and infants of less than 2 years old should be made by consistently positive nucleic acid test results, such as the presence of HIV-2 DNA/RNA (FHV2Q / HIV-2 DNA/RNA Qualitative Real-Time PCR).


New York State clients: This test should not be requested for maternal/newborn HIV screening on specimens originating in New York State, due to state regulatory requirements for expedited result reporting.

Necessary Information

Date of collection is required.

Specimen Required

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions:

1. Centrifuge blood collection tube per collection tube manufacturer's instructions (eg, centrifuge and aliquot within 2 hours of collection for BD Vacutainer tubes).

2. Aliquot serum into plastic vial.

Specimen Minimum Volume

0.2 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Frozen (preferred) 30 days
  Refrigerated  14 days
  Ambient  48 hours

Reference Values


Day(s) Performed

Monday through Friday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
HIV2L HIV-2 Ab Confirmation, S 81641-3


Result ID Test Result Name Result LOINC Value
61785 HIV-2 Ab Confirmation, S 81641-3

Test Classification

This test has been cleared, approved or is exempt by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

Report Available

1 to 3 days

NY State Approved