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Test ID HLA58 HLA-B*5801 Genotype, Allopurinol Hypersensitivity, Blood

Useful For

Identifying individuals with an increased risk of severe cutaneous adverse reactions to allopurinol based on the presence of the human leukocyte antigen HLA-B*58:01 allele

Method Name

Qualitative Allele-Specific Real-Time Polymerase Chain Reaction (PCR)

Reporting Name

HLA-B 5801 Genotype, Allopurinol, B

Specimen Type

Whole Blood EDTA


Specimen Required


Multiple genotype tests can be performed on a single specimen after a single extraction. See Multiple Whole Blood EDTA Genotype Tests in Special Instructions for a list of tests that can be ordered together.

 

Container/Tube: Lavender top (EDTA)

Specimen Volume: 3 mL

Collection Instructions: Send specimen in original tube.


Specimen Minimum Volume

0.35 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Whole Blood EDTA Ambient (preferred)
  Refrigerated 

Reference Values

An interpretive report will be provided.

Day(s) and Time(s) Performed

Monday, Wednesday, Friday; 9 a.m.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

81381

LOINC Code Information

Test ID Test Order Name Order LOINC Value
HLA58 HLA-B 5801 Genotype, Allopurinol, B 79711-8

 

Result ID Test Result Name Result LOINC Value
35101 HLA-B 5801 Result 79711-8
35102 HLA-B 5801 Interpretation 69047-9
35103 Reviewed by 18771-6

Test Classification

This test was developed using an analyte specific reagent. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

NY State Approved

Yes

Forms

1. New York Clients-Informed consent is required. Document on the request form or electronic order that a copy is on file. The following documents are available in Special Instructions:

-Informed Consent for Genetic Testing (T576)

-Informed Consent for Genetic Testing-Spanish (T826)

2. If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-Pharmacogenomics Test Request (T797)

-Therapeutics Test Request (T831)