Sign in →

Test ID HMCRU Heavy Metal/Creatinine Ratio, with Reflex, Urine


Specimen Required


Patient Preparation:

-Patient should not eat seafood for a 48-hour period prior to start of collection.

-High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.

Supplies: Urine Tubes, 10 mL (T068)

Collection Container/Tube: Clean, plastic urine container with no metal cap or glued insert

Submission Container/Tube: Plastic, 10-mL urine tube (T068) or clean, plastic aliquot container with no metal cap or glued insert

Specimen Volume: 6 mL

Collection Instructions:

1. Collect a random urine specimen.

2. See Trace Metals Analysis Specimen Collection and Transport in Special Instructions for complete instructions.


Useful For

Preferred screening test for detection of arsenic, cadmium, mercury, and lead in random urine specimens

Profile Information

Test ID Reporting Name Available Separately Always Performed
ARSC Arsenic/Creatinine Ratio, U Yes, (order ARSCR) Yes
CDRC Cadmium/Creatinine Ratio, U Yes, (order CDRCR) Yes
HGRC Mercury/Creatinine Ratio, U Yes, (order HGRCR) Yes
PBRC Lead/Creatinine Ratio, U Yes, (order PBRCR) Yes
CDCR Creatinine Conc No Yes

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
ASFRU Arsenic Fractionation, Random, U Yes No

Testing Algorithm

If arsenic concentration is greater than or equal to 35 mcg/L, then fractionation will be performed at an additional charge.

 

See Porphyria (Acute) Testing Algorithm in Special Instructions.

Method Name

ARSC, CDRC, HGRC, and PBRC: Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)

CDCR: Enzymatic Colorimetric Assay

Reporting Name

Heavy Metal/Creat Ratio, w/Reflex,U

Specimen Type

Urine

Specimen Minimum Volume

3 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 7 days
  Frozen  7 days

Reference Values

ARSENIC/CREATININE:

0-17 years: not established

≥18 years: <24 mcg/g creatinine

 

CADMIUM/CREATININE:

0-17 years: not established

≥18 years: <0.6 mcg/g creatinine

 

MERCURY/CREATININE:

0-17 years: not established

≥18 years: <2 mcg/g creatinine

 

LEAD/CREATININE:

0-17 years: not established

≥18 years: <2 mcg/g creatinine

Day(s) and Time(s) Performed

Monday through Friday; 7 p.m.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

See Individual Test IDs

CPT Code Information

82175

82300

83825

83655

82570

LOINC Code Information

Test ID Test Order Name Order LOINC Value
HMCRU Heavy Metal/Creat Ratio, w/Reflex,U In Process

 

Result ID Test Result Name Result LOINC Value
48544 Cadmium/Creatinine Ratio, U 13471-8
48546 Mercury/Creatinine Ratio, U 13465-0
48548 Lead/Creatinine Ratio, U 13466-8
CDCR Creatinine Conc 2161-8
48541 Arsenic/Creatinine Ratio, U 13463-5
48542 Arsenic Concentration w/Reflex 5586-3