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Test ID HMUCR Heavy Metal/Creatinine Ratio, with Reflex, Random, Urine


Specimen Required


Patient Preparation:

-Patient should not eat seafood for a 48-hour period prior to start of collection.

-High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.

Supplies: Urine Tubes, 10 mL (T068)

Collection Container/Tube: Clean, plastic urine container with no metal cap or glued insert

Submission Container/Tube: Plastic, 10-mL urine tube  or clean, plastic aliquot container with no metal cap or glued insert

Specimen Volume: 6 mL

Collection Instructions:

1. Collect a random urine specimen.

2. See Trace Metals Analysis Specimen Collection and Transport in Special Instructions for complete instructions.


Useful For

Preferred screening test for detection of arsenic, cadmium, mercury, and lead in random urine specimens

Profile Information

Test ID Reporting Name Available Separately Always Performed
ASCU Arsenic/Creatinine Ratio, U Yes, (order ASUCR) Yes
CDCU Cadmium/Creatinine Ratio, U Yes, (order CDUCR) Yes
HGCU Mercury/Creatinine Ratio, U Yes, (order HGUCR) Yes
PBCU Lead/Creatinine Ratio, U Yes, (order PBUCR) Yes
CRETR Creatinine, Random, U No Yes

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
SPAS Arsenic Speciation, Random, U Yes No

Testing Algorithm

If the total arsenic concentration is 10 mcg/L or greater, then speciation will be performed at an additional charge.

 

See Porphyria (Acute) Testing Algorithm in Special Instructions.

Method Name

ASCU, CDCU, HGCU, PBCU: Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)

CRETR: Enzymatic Colorimetric Assay

Reporting Name

Heavy Metal/Creat Ratio,w/Reflex,U

Specimen Type

Urine

Specimen Minimum Volume

3 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 7 days
  Frozen  7 days

Reference Values

ARSENIC/CREATININE:

0-17 years: not established

≥18 years: <24 mcg/g creatinine

 

CADMIUM/CREATININE:

0-17 years: not established

≥18 years: <0.6 mcg/g creatinine

 

MERCURY/CREATININE:

0-17 years: not established

≥18 years: <2 mcg/g creatinine

 

LEAD/CREATININE:

0-17 years: not established

≥18 years: <2 mcg/g creatinine

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

82175

82300

83825

83655

82570

LOINC Code Information

Test ID Test Order Name Order LOINC Value
HMUCR Heavy Metal/Creat Ratio,w/Reflex,U 29589-9

 

Result ID Test Result Name Result LOINC Value
608902 Cadmium/Creatinine Ratio, U 13471-8
608903 Mercury/Creatinine Ratio, U 13465-0
608904 Lead/Creatinine Ratio, U 13466-8
CRETR Creatinine, Random, U 2161-8
608900 Arsenic/Creatinine Ratio, U 13463-5
608901 Total Arsenic Concentration 5586-3

NY State Approved

Yes