Test ID LCMSP Microsporidia species, Molecular Detection, PCR, Varies
Useful For
Detection of Enterocytozoon bieneusi and Encephalitozoon species in fecal and urine specimens to support the clinical diagnosis of microsporidiosis
Highlights
This test is intended to be used for immunocompromised patients with persistent, watery diarrhea. See the Parasitic Investigation of Stool Specimens Algorithm.
This test is intended to be used for the detection of Enterocytozoon bieneusi and Encephalitozoon species DNA in fecal and urine specimens to support the clinical diagnosis of microsporidiosis. Other sources should be tested using MTBS / Microsporidia Stain, Varies.
A negative result indicates the absence of detectable DNA from Enterocytozoon bieneusi and Encephalitozoon species in the specimen, but does not rule out ongoing microsporidiosis. See Interpretation for more information.
Special Instructions
Method Name
Real-Time Polymerase Chain Reaction (PCR)/DNA Probe Hybridization
Reporting Name
Microsporidia PCRSpecimen Type
VariesAdvisory Information
For specimens other than feces or urine, MTBS / Microsporidia Stain, Varies should be ordered since it will detect other microsporidia that are not targeted by this assay.
Necessary Information
Specimen source is required.
Specimen Required
Submit only 1 of the following specimens:
Preferred:
Specimen Type: Unpreserved feces
Supplies: Stool container, Small (Random), 4 oz (T288); Stool Collection Kit, Random (T635)
Container/Tube: Fecal container (T288)
Specimen Volume: 5 g
Specimen Type: Preserved feces
Supplies: ECOFIX Stool Transport Vial (Kit) (T219); Stool Collection Kit, Random (T635)
Container/Tube: ECOFIX preservative
Specimen Volume: 5 g
Specimen Type: Urine
Container/Tube: Sterile container
Specimen Volume: 5 mL
Collection Instructions: Mid-stream, clean-catch, suprapubic aspirates and catheterization collections are acceptable. Please submit in a clean, sterile container free from preservatives. The first portion of the voided urine (first void) is also acceptable.
Specimen Minimum Volume
Feces: 1 g
Urine: 0.5 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Varies | Refrigerated (preferred) | 7 days | |
Ambient | 7 days | ||
Frozen | 7 days |
Reference Values
Negative
Day(s) and Time(s) Performed
Tuesday through Friday; 6 a.m.
Performing Laboratory

CPT Code Information
87798
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
LCMSP | Microsporidia PCR | 94332-4 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
MSPS | Specimen Source | 31208-2 |
36744 | Encephalitozoon species | 94333-2 |
36745 | Enterocytozoon bieneusi | 94334-0 |
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.Testing Algorithm
The following algorithms are available in Special Instructions:
NY State Approved
YesForms
If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:
-Microbiology Test Request (T244)