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Test ID LEFLU Leflunomide Metabolite (Teriflunomide), Serum

Useful For

Therapeutic monitoring of patients actively taking leflunomide

 

Assessment of elimination in patients requiring enhanced elimination of the drug

Method Name

High-Turbulence Liquid Chromatography Mass Spectrometry (HTLC-MS/MS)

Reporting Name

Leflunomide Metabolite, S

Specimen Type

Serum Red


Specimen Required


Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Draw blood no sooner than 12 hours (trough value) after last dose.

2. Spin down within 2 hours of draw.


Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Ambient (preferred) 28 days
  Frozen  28 days
  Refrigerated  28 days

Reference Values

Therapeutic: >40 mcg/mL

Elimination: <0.020 mcg/mL

Day(s) and Time(s) Performed

Monday, Wednesday, Friday; 4 p.m.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

80299

LOINC Code Information

Test ID Test Order Name Order LOINC Value
LEFLU Leflunomide Metabolite, S 44828-2

 

Result ID Test Result Name Result LOINC Value
60292 Leflunomide Metabolite, S 44828-2

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.