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Test ID MMAU Methylmalonic Acid, Quantitative, Urine

Useful For

Evaluating children with signs and symptoms of methylmalonic acidemia


Evaluating individuals with signs and symptoms associated with a variety of causes of cobalamin deficiency

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

Methylmalonic Acid, QN, U

Specimen Type


Specimen Required

Patient Preparation: Overnight fast required

Supplies: Urine Tubes, 10 mL (T068)

Container/Tube: Plastic, 10-mL urine tube (T068)

Specimen Volume: 4 mL

Collection Instructions: Collect second-voided specimen after an overnight fast.

Specimen Minimum Volume

1.2 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Frozen (preferred) 28 days
  Refrigerated  28 days
  Ambient  21 days

Reference Values

<3.60 mmol/mol creatinine

Day(s) Performed

Monday through Friday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
MMAU Methylmalonic Acid, QN, U 25116-5


Result ID Test Result Name Result LOINC Value
80290 Methylmalonic Acid, QN, U 25116-5

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

Report Available

3 to 5 days

NY State Approved



If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-Benign Hematology Test Request Form (T755)

-Inborn Errors of Metabolism Test Request (T798)