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Test ID MPLVA MPL Exon 10 Mutation Detection, Varies

Useful For

Aiding in the distinction between a reactive cytosis and a myeloproliferative neoplasm

Method Name

Mutation Detection in DNA Using Sanger Sequencing

Reporting Name

MPL Exon 10 Mutation Detection, V

Specimen Type


Specimen Required

Specimen Type: Extracted DNA from blood or bone marrow

Container/Tube: 1.5- to 2- mL tube

Specimen Volume: Entire specimen

Collection Instructions: Label specimen as extracted DNA from blood or bone marrow and provide indication of volume and concentration of DNA.

Specimen Stability Information: Refrigerated/Ambient

Specimen Stability Information

Specimen Type Temperature Time
Varies Varies

Reference Values

An interpretive report will be provided.

Day(s) and Time(s) Performed

Monday through Friday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

81403-MPL (myeloproliferative leukemia virus oncogene, thrombopoietin receptor, TPOR) (eg, myeloproliferative disorder), exon 10 sequence

LOINC Code Information

Test ID Test Order Name Order LOINC Value
MPLVA MPL Exon 10 Mutation Detection, V In Process


Result ID Test Result Name Result LOINC Value
34850 Final Diagnosis: 34574-4
34937 Specimen: 31208-2

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

NY State Approved


Testing Algorithm

See Myeloproliferative Neoplasm: A Diagnostic Approach to Bone Marrow Evaluation in Special Instructions.


1. Hematopathology Patient Information (T676) in Special Instructions

2. If not ordering electronically, complete, print, and send a Hematopathology/Cytogenetics Test Request (T726) with the specimen.