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Test ID MPSU Monoclonal Protein Study, 24 Hour, Urine

Useful For

Monitoring patients with monoclonal gammopathies using 24-hour urine specimens

Method Name

PTU: Turbidimetry

PEU: Agarose Gel Electrophoresis

IFXU: Immunofixation

Reporting Name

Monoclonal Protein Study, U

Specimen Type

Urine


Shipping Instructions


Refrigerate specimen during collection and send refrigerated.



Necessary Information


24-Hour volume is required.



Specimen Required


Supplies: Aliquot Tube, 5 mL (T465)

Submission Container/Tube: Plastic, 60-mL urine bottle and plastic, 5-mL tube

Specimen Volume: 50 mL

Collection Instructions:

1. Collect urine for 24 hours.

2. Aliquot specimen between containers.

3. Label specimens appropriately (60-mL bottle for protein electrophoresis and immunofixation and 5-mL tube for protein, total).

Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens in Special Instructions for multiple collections.


Specimen Minimum Volume

25 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 14 days
  Frozen  5 days
  Ambient  72 hours

Reference Values

PROTEIN, TOTAL

<229 mg/24 hours

Reference values have not been established for patients <18 years of age.

Reference value applies to 24-hour collection.

 

ELECTROPHORESIS, PROTEIN

The following fractions, if present, will be reported as a percent of the protein, total.

Albumin

Alpha-1-globulin

Alpha-2-globulin

Beta-globulin

Gamma globulin

Day(s) and Time(s) Performed

Protein, Total: Monday through Sunday; Continuously

Electrophoresis, Protein: Monday through Saturday; 12 p.m.

Immunofixation: Monday through Saturday; 8 a.m.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

84156

84166

86335

LOINC Code Information

Test ID Test Order Name Order LOINC Value
MPSU Monoclonal Protein Study, U In Process

 

Result ID Test Result Name Result LOINC Value
82025 Immunofixation, U 33042-3
2776 Albumin 13986-5
TP2 Total Protein 2889-4
TM23 Collection Duration 13362-9
2777 Alpha 1-Globulin 13984-0
2779 Alpha 2-Globulin 13987-3
VL21 Urine Volume 19153-6
CONC1 Concentration 57369-1
2780 Beta-Globulin 13988-1
2781 Gamma-Globulin 13989-9
2833 A/G Ratio 44294-7
21446 M spike 42482-0
22307 M spike 42482-0
21447 Impression 32210-7

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

NY State Approved

Yes

Testing Algorithm

The following algorithms are available in Special Instructions:

-Laboratory Approach to the Diagnosis of Amyloidosis

-Laboratory Screening Tests for Suspected Multiple Myeloma

Profile Information

Test ID Reporting Name Available Separately Always Performed
PTU Protein, Total, U Yes Yes
PEU Protein Electrophoresis, U No Yes
IFXU Immunofixation, U No Yes

Urine Preservative Collection Options

Note: The addition of preservative or application of temperature controls must occur within 4 hours of completion of the collection.

Ambient

Yes

Refrigerate

Preferred

Frozen

Yes

50% Acetic Acid

No

Boric Acid

No

Diazolidinyl Urea

No

6M Hydrochloric Acid

No

6M Nitric Acid

No

Sodium Carbonate

No

Thymol

Yes

Toluene

No

 

Forms

If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.