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Test ID NMH1D N-Methylhistamine, 24 Hour, Urine


Advisory Information


A random urine collection is preferred for patients with episodic symptoms, for example in the context of allergic reactions, brought on by specific environmental factors. See NMHR / N-Methylhistamine, Random, Urine.



Specimen Required


Only orderable as part of a profile. For more information see:

NMH24 / N-Methylhistamine, 24 Hour, Urine

 

Supplies: Aliquot Tube, 5 mL (T465)

Container/Tube: Plastic, 5-mL tube (T465)

Specimen Volume: 5 mL

Collection Instructions:

1. Collect urine for 24 hours.

2. No preservative.

Additional Information:

See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens in Special Instructions for multiple collections.


Useful For

Screening for and monitoring of mastocytosis and disorders of systemic mast-cell activation, such as anaphylaxis and other forms of severe systemic allergic reactions as a part of a profile

 

Monitoring therapeutic progress in conditions that are associated with secondary, localized, low-grade persistent, mast-cell proliferation and activation such as interstitial cystitis

Method Name

Only orderable as part of a profile. For more information see:

NMH24 / N-Methylhistamine, 24 Hour, Urine

 

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

N-Methylhistamine, 24 Hr, U

Specimen Type

Urine

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Reference Values

Only orderable as part of a profile. For more information see:

NMH24 / N-Methylhistamine, 24 Hour, Urine

 

0-5 years: 120-510 mcg/g creatinine

6-16 years: 70-330 mcg/g creatinine

>16 years: 30-200 mcg/g creatinine

Day(s) and Time(s) Performed

Tuesday, Thursday; 10 a.m.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

82542

LOINC Code Information

Test ID Test Order Name Order LOINC Value
NMH1D N-Methylhistamine, 24 Hr, U 44340-8

 

Result ID Test Result Name Result LOINC Value
605159 N-Methylhistamine, 24 Hr 44340-8

NY State Approved

Yes

Urine Preservative Collection Options

Note: The addition of preservative or application of temperature controls must occur within 4 hours of completion of the collection.

Ambient

Yes

Refrigerate

Preferred

Frozen

Yes

50% Acetic Acid

Yes

Boric Acid

Yes

Diazolidinyl Urea

No

6M Hydrochloric Acid

Yes

6M Nitric Acid

Yes

Sodium Carbonate

Yes

Thymol

No

Toluene

No