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Test ID NSYPH Syphilis IgG Enzyme Immunoassay, Serum

Specimen Required

Collection Container/Tube: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.6 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial.

Useful For

An aid in the diagnosis of infection with Treponema pallidum


Routine prenatal screening


This test is not useful for diagnosis of congenital syphilis.


This test is not offered as a screening or confirmatory test for blood donor specimens.


This testing should be used to assess for recent or past infection with Treponema pallidum or for routine prenatal screening.


Testing for syphilis is performed using the reverse screening algorithm at Mayo Clinic and Mayo Clinic Laboratories.

Method Name

Enzyme Immunoassay (EIA)

Reporting Name

Syphilis IgG EIA, S

Specimen Type


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Frozen 14 days

Reference Values


Reference values apply to all ages

Day(s) Performed

Monday through Friday, Sunday

Report Available

Same day/1 to 3 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
NSYPH Syphilis IgG EIA, S 47238-1


Result ID Test Result Name Result LOINC Value
NSYPH Syphilis IgG EIA, S 47238-1

NY State Approved



If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.